International Academic Journals

Plant species genetics, cell culture, Elisa kits, antibodies

Insights into the conformation and self-association of a concentrated monoclonal antibody using isothermal chemical denaturation and nuclear magnetic resonance

The aim of this investigation was to spotlight the utility of nuclear magnetic resonance (NMR) as a multi-attribute methodology for the characterization of therapeutic antibodies. On this case examine, we in contrast outcomes from isothermal chemical denaturation (ICD) and NMR with commonplace strategies to narrate conformational states of a mannequin monoclonal antibody (mAb1) with protein-protein interactions (PPI) that result in self -...