International Academic Journals

Plant species genetics, cell culture, Elisa kits, antibodies

Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer

Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer
Within the midst of the COVID-19 pandemic, adaptive options are wanted to permit us to make quick selections and take efficient sanitation measures, e.g., the quick screening of enormous teams (workers, passengers, pupils, and many others.). Though being dependable, a lot of the present SARS-CoV-2 detection strategies can’t be built-in into clothes for use on demand. Right here, we report an natural field-effect transistor (OFET)-based biosensing gadget detecting of each SARS-CoV-2 antigens and anti-SARS-CoV-2 antibodies in lower than 20 min.
The biosensor was produced by functionalizing an intrinsically stretchable and semiconducting triblock copolymer (TBC) movie both with the anti-S1 protein antibodies (S1 Abs) or receptor-binding area (RBD) of the S1 protein, focusing on CoV-2-specific RBDs and anti-S1 Abs, respectively. The obtained sensing platform is simple to comprehend because of the easy fabrication of the TBC movie and the utilization of the dependable bodily adsorption method for the molecular immobilization.
The gadget demonstrates a excessive sensitivity of about 19%/dec and a restrict of detection (LOD) of 0.36 fg/mL for anti-SARS-Cov-2 antibodies and, on the similar time, a sensitivity of 32%/dec and a LOD of 76.61 pg/mL for the virus antigen detection. The TBC used as energetic layer is tender, has a low modulus of 24 MPa, and will be stretched as much as 90% with no crack formation of the movie. The TBC is suitable with roll-to-roll printing, doubtlessly enabling the fabrication of low-cost wearable or on-skin diagnostic platforms aiming at point-of-care ideas.

Drug-to-Antibody Ratio Estimation by way of Proteoform Peak Integration within the Evaluation of Antibody-Oligonucleotide Conjugates with Orbitrap Fourier Rework Mass Spectrometry

The therapeutic efficacy and pharmacokinetics of antibody-drug conjugates (ADCs) on the whole, and antibody-oligonucleotide conjugates (AOCs) particularly, rely upon the drug-to-antibody ratio (DAR) distribution and common worth. The DAR is taken into account a vital high quality attribute, and knowledge pertaining to it must be gathered throughout ADC/AOC growth, manufacturing, and storage.
Nevertheless, due to the excessive structural complexity of ADC/AOC samples, notably within the preliminary drug-development phases, the appliance of the present state-of-the-art mass spectrometric approaches will be restricted for DAR evaluation.
Right here, we reveal a novel strategy for the evaluation of advanced ADC/AOC samples, following native size-exclusion chromatography Orbitrap Fourier rework mass spectrometry (FTMS). The strategy is predicated on the mixing of the proteoform-level mass spectral peaks as a way to present an estimate of the DAR distribution and its common worth with lower than 10% error.
The height integration is carried out by way of a truncation of the Orbitrap’s unreduced time-domain ion alerts (transients) earlier than mass spectra technology by way of FT processing. Transient recording and processing are undertaken utilizing an exterior knowledge acquisition system, FTMS Booster X2, coupled to a Q Exactive HF Orbitrap FTMS instrument.
This strategy has been utilized to the evaluation of complete and subunit-level trastuzumab conjugates with oligonucleotides. The obtained outcomes point out that ADC/AOC pattern purification or simplification procedures, for instance, deglycosylation, might be omitted or minimized previous to the DAR evaluation, streamlining the drug-development course of.

Growth of a novel reporter gene assay to judge antibody-dependent mobile phagocytosis for anti-CD20 therapeutic antibodies

Greater than 100 monoclonal antibodies (mAbs) have been permitted by FDA. The mechanism of motion (MoA) entails in neutralization of a selected goal by way of the Fab area and Fc effector features by way of Fc area, whereas the latter embrace complement-dependent cytotoxicity (CDC), antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent mobile phagocytosis (ADCP).
ADCP has been acknowledged one of the crucial necessary MoAs, particularly for anti-cancer mAbs lately. Nevertheless, conventional bioassays measuring ADCP all the time launched main macrophages and move cytometry, that are troublesome to deal with and extremely variable.
On this research, we engineered a monoclonal Jurkat/NFAT/CD32a-FcεRIγ effector cell line that stably expresses CD32a-FcεRIγ chimeric receptor and NFAT-controlled luciferase. The corresponding mAb may bind with the membrane antigens on the goal cells with its Fab fragment and CD32a-FcεRIγ on the effector cells with its Fc fragment, resulting in the crosslinking of CD32a-FcεRIγ and the resultant expression of subsequent NFAT-controlled luciferase, which represents the bioactivity of ADCP primarily based on the MoA of the mAb.
With rituximab because the mannequin mAb, Raji cells because the goal cells, and Jurkat/NFAT/CD32a-FcεRIγ cells because the effector cells, we adopted the technique of Design of Experiment (DoE) to optimize the bioassay. Then we totally validated the established bioassay based on ICH-Q2(R1), which proved the nice assay efficiency traits of the bioassay, together with specificity, accuracy, precision, linearity, stability and robustness.
This RGA will be utilized to judge the -ADCP bioactivity for anti-CD20 mAbs in lot launch, stability testing in addition to biosimilar comparability. The engineered cells may additionally doubtlessly be used to judge the ADCP bioactivity of mAbs with different targets.

Liquid chromatography-mass spectrometry methodology for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum

Liquid chromatography tandem mass spectrometry (LC-MS/MS) has regularly grow to be a promising various to ligand binding assay for the bioanalysis of biotherapeutic molecules, as a result of its speedy methodology growth and excessive accuracy. On this research, we established a brand new LC-MS/MS methodology for the willpower of the anti-sclerostin monoclonal antibody (SHR-1222) in cynomolgus monkey serum, and in contrast it to a earlier electrochemiluminescence methodology. The antibody was quantified by detecting the surrogate peptide obtained by trypsin digestion.
The surrogate peptide was rigorously chosen by investigating its uniqueness, stability and MS response. The quantitative vary of the proposed methodology was 2.00-500 μg/mL, and this verified methodology was efficiently utilized to the toxicokinetic evaluation of SHR-1222 in cynomolgus monkey serum. It was discovered that the concentrations of SHR-1222 in cynomolgus monkeys displayed a wonderful settlement between the LC-MS/MS and electrochemiluminescence strategies (ratios of drug publicity, 0.8-1.0).

Mouse Monoclonal antibody AntiCCND2

CCND2ACMO 0,1 mg
EUR 349

EFHD1 Mouse Monoclonal Antibody

38043-100ul 100ul
EUR 252

EFHD1 Mouse Monoclonal Antibody

38043-50ul 50ul
EUR 187

HSV Mouse Monoclonal Antibody

38056-100ul 100ul
EUR 252

HSV Mouse Monoclonal Antibody

38056-50ul 50ul
EUR 187

HSP90β Mouse Monoclonal Antibody

38066-100ul 100ul
EUR 252

HSP90β Mouse Monoclonal Antibody

38066-50ul 50ul
EUR 187

PARP Mouse Monoclonal Antibody

38067-100ul 100ul
EUR 252

PARP Mouse Monoclonal Antibody

38067-50ul 50ul
EUR 187

EGFR Mouse Monoclonal Antibody

38070-100ul 100ul
EUR 252

EGFR Mouse Monoclonal Antibody

38070-50ul 50ul
EUR 187

eIF4A1 Mouse Monoclonal Antibody

38072-100ul 100ul
EUR 252

eIF4A1 Mouse Monoclonal Antibody

38072-50ul 50ul
EUR 187

Fibronectin Mouse Monoclonal Antibody

38073-100ul 100ul
EUR 252

Fibronectin Mouse Monoclonal Antibody

38073-50ul 50ul
EUR 187

mStrawberry Mouse Monoclonal Antibody

38099-100ul 100ul
EUR 252

mStrawberry Mouse Monoclonal Antibody

38099-50ul 50ul
EUR 187

eNOS Mouse Monoclonal Antibody

38100-100ul 100ul
EUR 252

eNOS Mouse Monoclonal Antibody

38100-50ul 50ul
EUR 187

PCNA Mouse Monoclonal Antibody

37978-100ul 100ul
EUR 252

PCNA Mouse Monoclonal Antibody

37978-50ul 50ul
EUR 187

EGFR Mouse Monoclonal Antibody

37996-100ul 100ul
EUR 252

EGFR Mouse Monoclonal Antibody

37996-50ul 50ul
EUR 187

CD20 Mouse Monoclonal Antibody

38003-100ul 100ul
EUR 252

CD20 Mouse Monoclonal Antibody

38003-50ul 50ul
EUR 187

CD23 Mouse Monoclonal Antibody

38004-100ul 100ul
EUR 252

CD23 Mouse Monoclonal Antibody

38004-50ul 50ul
EUR 187

CD68 Mouse Monoclonal Antibody

38005-100ul 100ul
EUR 252

CD68 Mouse Monoclonal Antibody

38005-50ul 50ul
EUR 187

CK19 Mouse Monoclonal Antibody

38006-100ul 100ul
EUR 252

CK19 Mouse Monoclonal Antibody

38006-50ul 50ul
EUR 187

p53 Mouse Monoclonal Antibody

38007-100ul 100ul
EUR 252

p53 Mouse Monoclonal Antibody

38007-50ul 50ul
EUR 187

CK7 Mouse Monoclonal Antibody

38009-100ul 100ul
EUR 252

CK7 Mouse Monoclonal Antibody

38009-50ul 50ul
EUR 187

CK8 Mouse Monoclonal Antibody

38010-100ul 100ul
EUR 252

CK8 Mouse Monoclonal Antibody

38010-50ul 50ul
EUR 187

CK16 Mouse Monoclonal Antibody

38011-100ul 100ul
EUR 252

CK16 Mouse Monoclonal Antibody

38011-50ul 50ul
EUR 187

CDX2 Mouse Monoclonal Antibody

38012-100ul 100ul
EUR 252

CDX2 Mouse Monoclonal Antibody

38012-50ul 50ul
EUR 187

GFAP Mouse Monoclonal Antibody

38014-100ul 100ul
EUR 252

GFAP Mouse Monoclonal Antibody

38014-50ul 50ul
EUR 187

CD21 Mouse Monoclonal Antibody

38015-100ul 100ul
EUR 252

CD21 Mouse Monoclonal Antibody

38015-50ul 50ul
EUR 187

NSE Mouse Monoclonal Antibody

38021-100ul 100ul
EUR 252

NSE Mouse Monoclonal Antibody

38021-50ul 50ul
EUR 187

MAP2 Mouse Monoclonal Antibody

38022-100ul 100ul
EUR 252

MAP2 Mouse Monoclonal Antibody

38022-50ul 50ul
EUR 187

ABCB5 Mouse Monoclonal Antibody

38031-100ul 100ul
EUR 252

ABCB5 Mouse Monoclonal Antibody

38031-50ul 50ul
EUR 187

ERCC1 Mouse Monoclonal Antibody

38035-100ul 100ul
EUR 252

ERCC1 Mouse Monoclonal Antibody

38035-50ul 50ul
EUR 187

CK17 Mouse Monoclonal Antibody

38038-100ul 100ul
EUR 252

CK17 Mouse Monoclonal Antibody

38038-50ul 50ul
EUR 187

CD23 Mouse Monoclonal Antibody

38039-100ul 100ul
EUR 252

CD23 Mouse Monoclonal Antibody

38039-50ul 50ul
EUR 187

PCNA Mouse Monoclonal Antibody

21801-100ul 100ul
EUR 252

PCNA Mouse Monoclonal Antibody

21801-50ul 50ul
EUR 187

mCherry Mouse Monoclonal Antibody

T515-100ul 100ul
EUR 252

mCherry Mouse Monoclonal Antibody

T515-50ul 50ul
EUR 187

Mouse Anti Mouse Cd44 Monoclonal Antibody

CABT-46107MM 0.25 mg
EUR 663

Mouse Anti-GAPDH Monoclonal Antibody

AKR-001 100 µg
EUR 508
Description: Mouse Anti-GAPDH Monoclonal Antibody is Protein A purified and provided at 1 mg/mL. Suitable for Western blot or Immunostaining. 100 µg.

Mouse Anti-GFP Monoclonal Antibody

AKR-020 100 µg
EUR 508
Description: Mouse Anti-GFP Monoclonal Antibody is Protein A purified and provided at 1 mg/mL. Suitable for Western blot or Immunostaining. 100 µg.

Mouse Anti-RFP Monoclonal Antibody

AKR-021 100 µg
EUR 508
Description: Mouse Anti-RFP Monoclonal Antibody recognizes Tag-RFP, Turbo-RFP, mCherry and mOrange. Suitable for Western Blot, Dot Blot, Immunostaining or ELISA. Clone RF5R. 100 µg.

Mouse Anti Agrin Monoclonal Antibody

CABT-50791MA 0.2 mg
EUR 1334

Mouse Anti Huntingtin Monoclonal Antibody

CABT-51054MH 0.1 mg
EUR 715

Mouse Anti Atic Monoclonal Antibody

CABT-54798MA 0.1 mg
EUR 559

Mouse Anti Cdk4 Monoclonal Antibody

CABT-54824MC 0.1 mg
EUR 944

Mouse Anti-Galactomannan monoclonal antibody

CABT-B226 Supernatant, 5mL
EUR 710

Mouse Anti-GOLGA1 monoclonal antibody

CABT-B229 1mL
EUR 663

Mouse Anti-TNRC6A monoclonal antibody

CABT-B231 5mL
EUR 725

Mouse Anti-Homogalacturonan monoclonal antibody

CABT-B232 Supernatant, 5mL
EUR 710

Mouse Anti-Haptoglobin monoclonal antibody

CABT-BL8834 1.0 mg
EUR 991

Mouse Anti-Haptoglobin monoclonal antibody

CABT-BL8835 1.0 mg
EUR 991

Mouse Anti-Haptoglobin monoclonal antibody

CABT-BL8836 1.0 mg
EUR 991

Mouse Anti-Haptoglobin monoclonal antibody

CABT-BL8837 1.0 mg
EUR 991

Mouse Anti-PEDV monoclonal antibody

CABT-BL8885 1.0 mg
EUR 892

Mouse Anti-PEDV monoclonal antibody

CABT-BL8886 1.0 mg
EUR 892

Mouse Monoclonal antibody Anti CD177

CD177ACMO 0,1 mg
EUR 349

PCNA Mouse Monoclonal Conjugated Antibody

C21801 100ul
EUR 397

Mouse Monoclonal Antibody Anti-GST

GSTACMO 0,1 mg
EUR 204.7

Mouse Monoclonal antibody Anti-IL17D

IL17DACMO 0,1 mg
EUR 349

Mouse Monoclonal antibody Anti-IL7D

IL7ACMO 0,1 mg
EUR 349

Mouse Monoclonal Antibody Anti-IL8

IL8ACMO 0,1 mg
EUR 349

STAT1 Mouse Monoclonal Antibody (8H11)

ABM40261-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (8H11)

ABM40261-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (8H11)

ABM40261-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

JAK1 Mouse Monoclonal Antibody (7G6)

ABM40262-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of JAK1 at AA range of 960-1040
  • Applications tips:
Description: A monoclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of JAK1 at AA range of 960-1040

JAK1 Mouse Monoclonal Antibody (7G6)

ABM40262-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of JAK1 at AA range of 960-1040
  • Applications tips:
Description: A monoclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of JAK1 at AA range of 960-1040

JAK1 Mouse Monoclonal Antibody (7G6)

ABM40262-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of JAK1 at AA range of 960-1040
  • Applications tips:
Description: A monoclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of JAK1 at AA range of 960-1040

STAT1 Mouse Monoclonal Antibody (12E8)

ABM40264-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (12E8)

ABM40264-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (12E8)

ABM40264-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (5H7)

ABM40267-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (5H7)

ABM40267-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

STAT1 Mouse Monoclonal Antibody (5H7)

ABM40267-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of STAT1 at AA range of 640-720
  • Applications tips:
Description: A monoclonal antibody for detection of STAT1 from Human, Mouse, Rat. This STAT1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of STAT1 at AA range of 640-720

SGK1 Mouse Monoclonal Antibody (4D12)

ABM40269-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of SGK1 at AA range of 350-430
  • Applications tips:
Description: A monoclonal antibody for detection of SGK1 from Human, Mouse, Rat. This SGK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of SGK1 at AA range of 350-430

SGK1 Mouse Monoclonal Antibody (4D12)

ABM40269-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of SGK1 at AA range of 350-430
  • Applications tips:
Description: A monoclonal antibody for detection of SGK1 from Human, Mouse, Rat. This SGK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of SGK1 at AA range of 350-430

SGK1 Mouse Monoclonal Antibody (4D12)

ABM40269-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of SGK1 at AA range of 350-430
  • Applications tips:
Description: A monoclonal antibody for detection of SGK1 from Human, Mouse, Rat. This SGK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of SGK1 at AA range of 350-430

HDAC1 Mouse Monoclonal Antibody (4E1)

ABM40270-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of HDAC1
  • Applications tips:
Description: A monoclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of HDAC1

HDAC1 Mouse Monoclonal Antibody (4E1)

ABM40270-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of HDAC1
  • Applications tips:
Description: A monoclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of HDAC1

HDAC1 Mouse Monoclonal Antibody (4E1)

ABM40270-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of HDAC1
  • Applications tips:
Description: A monoclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of HDAC1

AKT Mouse Monoclonal Antibody (10D6)

ABM40272-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

AKT Mouse Monoclonal Antibody (10D6)

ABM40272-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

AKT Mouse Monoclonal Antibody (10D6)

ABM40272-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

Bax Mouse Monoclonal Antibody (6F11)

ABM40273-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat, Chicken. This Bax antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

Bax Mouse Monoclonal Antibody (6F11)

ABM40273-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat, Chicken. This Bax antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

Bax Mouse Monoclonal Antibody (6F11)

ABM40273-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat, Chicken. This Bax antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

AKT Mouse Monoclonal Antibody (1H2)

ABM40276-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

AKT Mouse Monoclonal Antibody (1H2)

ABM40276-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

AKT Mouse Monoclonal Antibody (1H2)

ABM40276-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of AKT at AA range of 400-480
  • Applications tips:
Description: A monoclonal antibody for detection of AKT from Human. This AKT antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of AKT at AA range of 400-480

Bax Mouse Monoclonal Antibody (1C1)

ABM40277-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat. This Bax antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

Bax Mouse Monoclonal Antibody (1C1)

ABM40277-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat. This Bax antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

Bax Mouse Monoclonal Antibody (1C1)

ABM40277-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of Bax at AA range of 30-110
  • Applications tips:
Description: A monoclonal antibody for detection of Bax from Human, Mouse, Rat. This Bax antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Bax at AA range of 30-110

TGFBeta1 Mouse Monoclonal Antibody (5D2)

ABM40279-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390

TGFBeta1 Mouse Monoclonal Antibody (5D2)

ABM40279-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390

TGFBeta1 Mouse Monoclonal Antibody (5D2)

ABM40279-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390

TGFBeta1 Mouse Monoclonal Antibody (10E5)

ABM40281-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Human, Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390

TGFBeta1 Mouse Monoclonal Antibody (10E5)

ABM40281-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Human, Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390

TGFBeta1 Mouse Monoclonal Antibody (10E5)

ABM40281-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide of TGF?1 at AA range of 310-390
  • Applications tips:
Description: A monoclonal antibody for detection of TGFBeta1 from Human, Mouse, Rat. This TGFBeta1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of TGF?1 at AA range of 310-390
Notably, two monkeys within the 60 mg/kg dose group had irregular profiles with a low detection worth of SHR-1222 of their particular person pattern. Combining the high-level anti-drug antibodies (ADAs) in these samples and the constant quantitative outcomes of the 2 strategies, we discovered that the decreased focus of SHR-1222 was because of the accelerated clearance mediated by ADAs quite than the interference of ADAs to the detection platform.
Taken collectively, we efficiently developed an correct, environment friendly and cost-effective LC-MS/MS methodology for the quantification of SHR-1222 in serum samples, which may function a strong device to enhance the preclinical growth of antibody medicine.

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