With the latest profitable concentrating on of B lymphocytes in sufferers with a number of sclerosis (MS), therapy with anti-CD20 monoclonal antibodies (mAbs) might characterize a promising managemental strategy, significantly for these with relapsing/remitting MS (RRMS).

A community meta-analysis was carried out based mostly on a complete search in Embase, PubMed, and the Cochrane Library to evaluate the comparative efficacy and security of at present obtainable anti-CD20 monoclonal antibodies (mAbs), together with rituximab, ocrelizumab, and ofatumumab, versus a standard comparator (interferon beta-1a [INFβ-1a]) in RRMS sufferers recruited in randomized medical trials (RCTs).

In a frequentist community meta-analytical mannequin, annualized relapse charges (ARRs) and security outcomes have been expressed as threat ratios (RRs), whereas relapse-free occasions have been expressed as odds ratios (ORs). Remedy rating was carried out utilizing P-scores. The knowledge of proof was appraised utilizing the GRADE strategy.

5 publications reported the outcomes of seven RCTs (3938 sufferers, 67.09% females). In comparison with INFβ-1a, ocrelizumab lowered the chance of ARR (RR = 0.56, 95% CI, 0.50-0.64), critical adversarial occasions (RR = 0.17, 95% CI, 0.09-0.30), and therapy discontinuation as a consequence of adversarial occasions (SAEs, RR = 0.60, 95% CI, 0.39-0.93), and it was related to larger odds of no relapses (OR = 2.47, 95% CI, 2.00-3.05).

Ocrelizumab ranked finest amongst all different remedies by way of lowering ARR and SAEs. The standard of proof was low for ocrelizumab, low to reasonable for rituximab, and excessive for ofatumumab. Additional large-sized, well-designed RCTs are wanted to corroborate the efficacy and security of ocrelizumab and different anti-CD20 mAbs in RRMS.

The fragment crystallizable (Fc) area of antibodies is answerable for their protecting perform and long-lasting serum half-life by way of Fc-mediated effector perform, transcytosis, and recycling by its interplay with Fc receptors (FcRs) expressed on varied immune leukocytes, epithelial, and endothelial cells. Due to this fact, the Fc-FcRs interplay is a management level of each endogenous and therapeutic antibody perform.

There are a variety of reported genetic variants of FcRs, which embrace polymorphisms in (i) extracellular area of FcRs, which change their affinities to Fc area of antibodies; (ii) each cytoplasmic and intracellular area, which alters the extent of sign transduction; and (iii) the promoter area of the FcRs gene, which impacts the expression degree of FcRs, thus being related to the pathogenesis of illness indications.

On this assessment, we firstly describe the correlation between the genetic variants of FcRs and immunological problems by particular person variations within the extent of FcRs-mediated laws. Secondly, we focus on the affect of the genetic variants of FcRs on the susceptibility to infectious ailments or most cancers within the perspective of FcRs-induced effector capabilities. General, we concluded that the genetic variants of FcRs are one of many key components within the design of antibody therapeutics as a consequence of their number of medical outcomes amongst people.

Sufferers with the monogenic immune dysregulatory syndrome autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), which is brought on by loss-of-function mutations within the autoimmune regulator (AIRE) gene, uniformly carry neutralizing autoantibodies directed in opposition to type-I interferons (IFNs) and lots of develop autoimmune pneumonitis, each of which place them at excessive threat for life-threatening COVID-19 pneumonia.

Bamlanivimab and etesevimab are monoclonal antibodies (mAbs) that focus on the SARS-CoV-2 spike protein and block entry of SARS-CoV-2 in host cells. Using bamlanivimab and etesevimab early throughout an infection was related to lowered COVID-19-associated hospitalization and dying in sufferers at excessive threat for progressing to extreme illness, which led the US Meals and Drug Administration to subject an emergency use authorization for his or her administration in non-hypoxemic, non-hospitalized high-risk sufferers.

Nevertheless, the protection and efficacy of those mAbs has not been evaluated in APECED sufferers. We enrolled two siblings with APECED on an IRB-approved protocol  and admitted them prophylactically on the NIH Medical Heart for analysis of mild-to-moderate COVID-19. We assessed the protection and medical results of early therapy with bamlanivimab and etesevimab.

The administration of bamlanivimab and etesevimab was effectively tolerated and was related to amelioration of COVID-19 signs and prevention of invasive ventilatory help, admission to the intensive care, and dying in each sufferers with out affecting the manufacturing of antibodies to the nucleocapsid protein of SARS-CoV-2.

If given early in the midst of COVID-19 an infection, bamlanivimab and etesevimab could also be useful in APECED and different high-risk sufferers with neutralizing autoantibodies directed in opposition to type-I IFNs.

Hepatocellular carcinoma (HCC) is an aggressive liver tumor that happens as a consequence of persistent liver illness, and it has a excessive mortality charge and restricted therapy choices. Immune checkpoint inhibitors have been efficiently launched and utilized in most cancers remedy, amongst which inhibitors of programmed dying ligand-1 (PD-L1) and its receptor programmed death-1 (PD-1) are generally administered for HCC as mixture remedy, together with mixed anti-angiogenic and immunotherapy mixture remedy.

We report a case of a main large HCC affected person with portal hepatic vein tumor thrombus who had a great response to atezolizumab together with bevacizumab, following development of illness on mixed immunotherapy with pembrolizumab and lenvatinib.

CD54 (pT512) Antibody
20-abx009840	Abbexa	EUR 376.80 EUR 560.40 EUR 243.60	100 ul 200 ul 30 ul

ICAM1 Antibody / CD54
RQ7001	NSJ Bioreagents	100 ug	EUR 356.15
Description: CD54, also known as ICAM-1 and Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1).

ICAM1 Antibody / CD54
RQ7002	NSJ Bioreagents	100 ug	EUR 356.15
Description: CD54, also known as ICAM-1 and Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1).

ICAM1 Antibody / CD54
RQ5121	NSJ Bioreagents	100ul	EUR 356.15
Description: The ICAM1 gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [RefSeq]

ICAM1 Antibody / CD54
V9194-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V9194-20UG	NSJ Bioreagents	20ug	EUR 153.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V9194SAF-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V9197-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes.

ICAM1 Antibody / CD54
V9197-20UG	NSJ Bioreagents	20ug	EUR 153.3
Description: ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes.

ICAM1 Antibody / CD54
V9197SAF-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes.

ICAM1 Antibody / CD54
V2604-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 mAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This mAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

ICAM1 Antibody / CD54
V2604-20UG	NSJ Bioreagents	20 ug	EUR 153.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 mAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This mAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

ICAM1 Antibody / CD54
V2604IHC-7ML	NSJ Bioreagents	7 ml	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 mAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This mAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

ICAM1 Antibody / CD54
V2604SAF-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 mAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This mAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

ICAM1 Antibody / CD54
V2605-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM1 also binds to CD43 and to Plasmodium falciparum infected RBCs and may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V2605-20UG	NSJ Bioreagents	20 ug	EUR 153.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM1 also binds to CD43 and to Plasmodium falciparum infected RBCs and may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V2605SAF-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM1 also binds to CD43 and to Plasmodium falciparum infected RBCs and may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V7851-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V7851-20UG	NSJ Bioreagents	20 ug	EUR 153.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

ICAM1 Antibody / CD54
V7851SAF-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

CD54 antibody (biotin)
61R-1516	Fitzgerald	100 ug	EUR 379.2
Description: Mouse monoclonal CD54 antibody (biotin)

CD54 Antibody (Biotin)
abx139537-01mg	Abbexa	0.1 mg	EUR 510

sICAM-1/CD54 ELISA Kit| Rat CD54 ELISA Kit
EF018233	Lifescience Market	96 Tests	EUR 826.8

CD54 Blocking Peptide
20-abx062764	Abbexa	EUR 326.40 EUR 493.20	1 mg 5 mg

Anti-Hu CD54 PE
1P-228-T025	ExBio	25 tests	EUR 168

Anti-Hu CD54 PE
1P-228-T100	ExBio	100 tests	EUR 288

Anti-Hu CD54 PE
1P-429-T025	ExBio	25 tests	EUR 168

Anti-Hu CD54 PE
1P-429-T100	ExBio	100 tests	EUR 288

Anti-Hu CD54 APC
1A-429-T025	ExBio	25 tests	EUR 168

Anti-Hu CD54 APC
1A-429-T100	ExBio	100 tests	EUR 288

Anti-Hu CD54 FITC
1F-429-T025	ExBio	25 tests	EUR 146.4

Anti-Hu CD54 FITC
1F-429-T100	ExBio	100 tests	EUR 244.8

Anti-Ms CD54 FITC
1F-625-C100	ExBio	0.1 mg	EUR 212.4

Anti-Hu CD54 PerCP
PC-429-T025	ExBio	25 tests	EUR 168

Anti-Hu CD54 PerCP
PC-429-T100	ExBio	100 tests	EUR 288

Anti-Hu CD54 Biotin
1B-429-C025	ExBio	0.025 mg	EUR 146.4

Anti-Hu CD54 Biotin
1B-429-C100	ExBio	0.1 mg	EUR 244.8

Anti-Hu CD54 Purified
11-228-C025	ExBio	0.025 mg	EUR 118.8

Anti-Hu CD54 Purified
11-228-C100	ExBio	0.1 mg	EUR 189.6

Anti-Hu CD54 Purified
11-229-C025	ExBio	0.025 mg	EUR 118.8

Anti-Hu CD54 Purified
11-229-C100	ExBio	0.1 mg	EUR 189.6

Anti-Ms CD54 Purified
11-625-C025	ExBio	0.025 mg	EUR 91.2

Anti-Ms CD54 Purified
11-625-C100	ExBio	0.1 mg	EUR 135.6

CD54 (pY512) Blocking Peptide
20-abx062763	Abbexa	EUR 376.80 EUR 610.80	1 mg 5 mg

CD54 (ICAM-1) Antibody (PE)
abx022366-100ug	Abbexa	100 ug	EUR 644.4

Anti-Hu CD54 Alexa Fluor700
A7-429-T025	ExBio	25 tests	EUR 184.8

Anti-Hu CD54 Alexa Fluor700
A7-429-T100	ExBio	100 tests	EUR 322.8

CD54 (ICAM-1) Antibody (Biotin)
abx022368-05mg	Abbexa	0.5 mg	EUR 861.6

CD54 (ICAM-1) Antibody (Biotin)
abx021458-02mg	Abbexa	0.2 mg	EUR 886.8

ICAM-1 / CD54 Recombinant Protein
11-541	ProSci	0.1 mg	EUR 714.3
Description: Inter-Cellular Adhesion Molecule 1 (ICAM-1) is also known as Cluster of Differentiation 54 (CD54), is a member of the immunoglobulin superfamily, and is a cell surface glycoprotein which is typically expressed in low concentrations on endothelial cells and cells of the immune system. The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFα) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies. ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.

CD54(ICAM-1) Monoclonal Antibody
27176-100ul	SAB	100ul	EUR 302.4

CD54(ICAM-1) Monoclonal Antibody
27176-50ul	SAB	50ul	EUR 224.4

Monoclonal CD54(ICAM-1) Antibody
AMM03141G	Leading Biology	0.1ml	EUR 580.8
Description: A Monoclonal antibody against Human CD54(ICAM-1). The antibodies are raised in Mouse. This antibody is applicable in WB

Monoclonal CD54(ICAM-1) Antibody
AMM03142G	Leading Biology	0.1ml	EUR 580.8
Description: A Monoclonal antibody against Human CD54(ICAM-1). The antibodies are raised in Mouse. This antibody is applicable in WB, ICC

Monoclonal ICAM-1 / CD54 Antibody
AMM01772G	Leading Biology	0.05mg	EUR 580.8
Description: A Monoclonal antibody against Human ICAM-1 / CD54. The antibodies are raised in Mouse. This antibody is applicable in IHC-P, IP, IHC-Fr, Flo

Rat ICAM-1/CD54 ELISA Kit
ERI0332	Abclonal	96Tests	EUR 625.2

Goat ICAM-1/CD54 ELISA Kit
EGTI0332	Abclonal	96Tests	EUR 625.2

Mouse ICAM-1/CD54 ELISA Kit
EMI0332	Abclonal	96Tests	EUR 625.2

Human ICAM-1/CD54 ELISA Kit
EHI0332	Abclonal	96Tests	EUR 625.2

Rabbit ICAM-1/CD54 ELISA Kit
ERTI0332	Abclonal	96Tests	EUR 625.2

Bovine ICAM-1/CD54 ELISA Kit
EBI0332	Abclonal	96Tests	EUR 625.2

Canine ICAM-1/CD54 ELISA Kit
ECI0332	Abclonal	96Tests	EUR 625.2

sICAM-1/CD54 ELISA KIT|Human
EF002065	Lifescience Market	96 Tests	EUR 826.8

Porcine ICAM-1/CD54 ELISA Kit
EPI0332	Abclonal	96Tests	EUR 625.2

CD54 / ICAM-1 (F4-31C2) Antibody
BNC401249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF640R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC401249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF640R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC551249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF555 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC551249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF555 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC431249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF543 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC431249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF543 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC471249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF647 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC471249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF647 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC801249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF680 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC801249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF680 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC811249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF680R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC811249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF680R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC611249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF660R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC611249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF660R conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCB1249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Biotin conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCB1249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Biotin conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNUM1249-50	Biotium	50uL	EUR 474
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), 1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCP1249-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), PerCP conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC941249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF594 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC941249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF594 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCAP1249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCAP1249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCA1249-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), APC conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCH1249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCH1249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNUB1249-100	Biotium	100uL	EUR 250.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Concentration: 0.2mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNUB1249-500	Biotium	500uL	EUR 549.6
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), Concentration: 0.2mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC041249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF405S conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC041249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF405S conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC051249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF405M conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC051249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF405M conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC701249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF770 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC701249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF770 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC881249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF488A conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC881249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF488A conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC681249-100	Biotium	100uL	EUR 238.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF568 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNC681249-500	Biotium	500uL	EUR 652.8
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), CF568 conjugate, Concentration: 0.1mg/mL

CD54 / ICAM-1 (F4-31C2) Antibody
BNCR1249-250	Biotium	250uL	EUR 459.6
Description: Primary antibody against CD54 / ICAM-1 ( F4-31C2), RPE conjugate, Concentration: 0.1mg/mL

Anserini ICAM-1/CD54 ELISA Kit
EAI0332	Abclonal	96Tests	EUR 625.2

Anti-Hu CD54 Purified Azide Free
10-429-C025	ExBio	0.025 mg	EUR 118.8

Anti-Hu CD54 Purified Azide Free
10-429-C100	ExBio	0.1 mg	EUR 189.6

Anti-Ms CD54 Purified Low Endotoxin
12-625-C100	ExBio	0.1 mg	EUR 178.8

ICAM-1(CD54) Mouse Monoclonal Antibody
Ab12144-100	GenDepot	100ul	EUR 578.4

VCAM-1(CD54) Mouse Monoclonal Antibody
Ab73313-050	GenDepot	50ul	EUR 562.8

VCAM-1(CD54) Mouse Monoclonal Antibody
Ab73313-100	GenDepot	100ul	EUR 724.8

Recombinant Human ICAM-1/CD54 Protein
RP00272	Abclonal	5 μg	EUR 163.2

Recombinant Mouse ICAM-1/CD54 Protein
RP01056	Abclonal	5 μg	EUR 163.2

Recombinant Mouse ICAM-1/CD54 Protein
RP01065	Abclonal	10 μg	EUR 231.6

Mouse Anti Human Cd54 Monoclonal Antibody
CABT-46474MH	Creative Diagnostics	0.2 mg	EUR 889.2

Mouse Anti Human Cd54 Monoclonal Antibody
CABT-49499MH	Creative Diagnostics	0.2 mg	EUR 982.8

Human CellExp? ICAM1 /CD54, human recombinant
7486-100	Biovision	each	EUR 861.6

Human CellExp? ICAM1 /CD54, human recombinant
7486-20	Biovision	each	EUR 320.4

Rabbit Anti Human Cd54 Polyclonal Antibody
CPBT-65044RH	Creative Diagnostics	0.1 mg	EUR 1057.2

Anti-ICAM1/Cd54 Rabbit Monoclonal Antibody
M00171-1	BosterBio	100ug/vial	EUR 476.4
Description: Rabbit Monoclonal ICAM1/Cd54 Antibody. Validated in IF, WB and tested in Human.

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx021457-02mg	Abbexa	0.2 mg	EUR 560.4

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx415026-02mg	Abbexa	0.2 mg	EUR 678

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx415028-25ug	Abbexa	25 ug	EUR 326.4

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx415520-02mg	Abbexa	0.2 mg	EUR 678

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx415521-05mg	Abbexa	0.5 mg	EUR 994.8

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx415524-01mg	Abbexa	0.1 mg	EUR 526.8

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx412166-01mg	Abbexa	0.1 mg	EUR 844.8

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx413013-05mg	Abbexa	0.5 mg	EUR 861.6

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx413228-02mg	Abbexa	0.2 mg	EUR 678

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx413229-05mg	Abbexa	0.5 mg	EUR 994.8

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx413232-01mg	Abbexa	0.1 mg	EUR 526.8

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx413235-20ug	Abbexa	20 ug	EUR 326.4

Intercellular Adhesion Molecule 1 (CD54) Antibody
20-abx134369	Abbexa	EUR 427.20 EUR 678.00 EUR 360.00	100 ul 200 ul 50 ul

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx139530-01mg	Abbexa	0.1 mg	EUR 427.2

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx139531-01mg	Abbexa	0.1 mg	EUR 427.2

Intercellular Adhesion Molecule 1 (CD54) Antibody
abx139532-01mg	Abbexa	0.1 mg	EUR 427.2

Intercellular Adhesion Molecule 1 (CD54) Antibody
20-abx009132	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

ELISA kit for Human sICAM-1 (CD54)
KET6003-48T	Abbkine	48T	EUR 242.4
Description: Quantitative sandwich ELISA for measuring Human sICAM-1 (CD54) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human sICAM-1 (CD54)
KET6003-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Human sICAM-1 (CD54) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human sICAM-1 (CD54)
KET6003-96T	Abbkine	96T	EUR 346.8
Description: Quantitative sandwich ELISA for measuring Human sICAM-1 (CD54) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Guinea Pig ICAM-1/CD54 ELISA Kit
EGI0332	Abclonal	96Tests	EUR 625.2

Mouse Anti Rat Cd54 Monoclonal Antibody,RPE
CABT-46486MR	Creative Diagnostics	100 TEST	EUR 920.4

CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)
6961-100	Biovision	each	EUR 444

CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)
6961-25	Biovision	each	EUR 235.2

CD54 [ICAM-1] non-lytic Recombinant Protein
90-396	ProSci	100 ug	EUR 651.3
Description: Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.

CD54 [ICAM-1] non-lytic Recombinant Protein
90-397	ProSci	50 ug	EUR 468.6
Description: Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.

Mouse Anti Human Cd54 Monoclonal Antibody,RPE
CABT-46472MH	Creative Diagnostics	100 TEST	EUR 852

Mouse Anti Human Cd54 Monoclonal Antibody,FITC
CABT-46466MH	Creative Diagnostics	0.1 mg	EUR 795.6

Rabbit Anti Human Cd54 Polyclonal Antibody,Biotin
CPBT-65043RH	Creative Diagnostics	50 µg	EUR 1057.2

Intercellular Adhesion Molecule 1 (CD54) Antibody (PE)
abx134368-100Assays	Abbexa	100 Assays	EUR 594

Intercellular Adhesion Molecule 1 (CD54) Antibody (PE)
abx134368-50Assays	Abbexa	50 Assays	EUR 477.6

Intercellular Adhesion Molecule 1 (CD54) Antibody (PE)
abx139533-100tests	Abbexa	100 tests	EUR 577.2

Intercellular Adhesion Molecule 1 (CD54) Antibody (PE)
abx139535-100tests	Abbexa	100 tests	EUR 577.2

Intercellular Adhesion Molecule 1 (CD54) Antibody (RPE)
abx413233-100tests	Abbexa	100 tests	EUR 710.4

Intercellular Adhesion Molecule 1 (CD54) Antibody (RPE)
abx413234-25tests	Abbexa	25 tests	EUR 376.8

Intercellular Adhesion Molecule 1 (CD54) Antibody (APC)
abx139536-100tests	Abbexa	100 tests	EUR 577.2

Intercellular Adhesion Molecule 1 (CD54) Antibody (FITC)
abx415027-100tests	Abbexa	100 tests	EUR 610.8

Intercellular Adhesion Molecule 1 (CD54) Antibody (FITC)
abx415522-01mg	Abbexa	0.1 mg	EUR 610.8

Intercellular Adhesion Molecule 1 (CD54) Antibody (FITC)
abx415523-05mg	Abbexa	0.5 mg	EUR 861.6

Intercellular Adhesion Molecule 1 (CD54) Antibody (FITC)
abx413230-01mg	Abbexa	0.1 mg	EUR 610.8

Intercellular Adhesion Molecule 1 (CD54) Antibody (FITC)
abx413231-25ug	Abbexa	25 ug	EUR 326.4

Human Intercellular Adhesion Molecule 1 (CD54) Protein
abx670234-50ug	Abbexa	50 ug	EUR 678

Intercellular Adhesion Molecule 1 (CD54) Antibody (PerCP)
abx139534-100tests	Abbexa	100 tests	EUR 577.2

Intercellular Adhesion Molecule 1 (CD54) Antibody (Biotin)
abx412167-50ug	Abbexa	50 ug	EUR 861.6

Nori® Rat ICAM-1/CD54 ELISA Kit
GR118330	Genorise Scientific	96-well	EUR 461

Nori® Human ICAM-1/CD54 ELISA Kit
GR111370	Genorise Scientific	96-well	EUR 461

Nori® Sheep ICAM-1/CD54 ELISA Kit
GR116343	Genorise Scientific	96-well	EUR 461

Nori® Mouse ICAM-1/CD54 ELISA Kit
GR117345	Genorise Scientific	96-well	EUR 461

This case demonstrates for the primary time that an HCC affected person who’s proof against anti-PD-1 antibody immunotherapy can profit from anti-PD-L1 antibody immunotherapy, offering a probably promising technique for the therapy of HCC.