Transcending towards Superior 3D-Cell Tradition Modalities: A Evaluate about an Rising Paradigm in Translational Oncology

Most cancers is a dysfunction characterised by an uncontrollable overgrowth and a fast-moving unfold of cells from a localized tissue to a number of organs of the physique, reaching a metastatic state. All through years, complexity of most cancers development and invasion, excessive prevalence and incidence, in addition to the excessive rise in remedy failure instances resulting in a poor affected person prognosis accounted for steady experimental investigations on animals and mobile fashions, primarily with 2D- and 3D-cell tradition. These days, these analysis fashions are thought of a most important asset to mirror the physiological occasions in lots of most cancers sorts when it comes to mobile traits and options, replication and metastatic mechanisms, metabolic pathways, biomarkers expression, and chemotherapeutic agent resistance.

In follow, primarily based on analysis perspective and speculation, scientists goal to decide on the perfect mannequin to method their understanding and to show their speculation. Not too long ago, 3D-cell fashions are seen to be extremely integrated as a vital instrument for reflecting the true most cancers cell microenvironment in pharmacokinetic and pharmacodynamics research, along with the depth of anticancer drug response in pharmacogenomics trials. Therefore, on this overview, we make clear the distinctive traits of 3D cells favoring its promising utilization by way of a comparative method with different analysis fashions, particularly 2D-cell tradition.

Plus, we are going to talk about the significance of 3D fashions as a direct reflector of the intrinsic most cancers cell surroundings with the most recent a number of strategies and kinds obtainable for 3D-cells implementation. We cultured the well-characterised SH-SY5Y human neural cell line to supply excessive purity cultures of cells differentiated to specific a neuronal phenotype, and designed a protocol to keep up these cells in tradition till they accrued biomarkers of mobile ageing.

Improvement of a Pig Mammary Epithelial Cell Tradition Mannequin as a Non-Scientific Instrument for Learning Epithelial Barrier-A Contribution from the IMI-ConcePTION Mission

The ConcePTION mission goals at producing additional data in regards to the dangers associated to the usage of treatment throughout breastfeeding, as this data is missing for mostly used medicine. Taking into account a number of points, the pig mannequin has been thought of by the consortium as essentially the most acceptable selection. The current analysis was deliberate to develop an environment friendly methodology for the isolation and tradition of porcine Mammary Epithelial Cells (pMECs) to review the mammary epithelial barrier in vitro. Mammary gland tissues had been collected at an area slaughterhouse, dissociated and the chosen mobile inhabitants was cultured, expanded and characterised by morphology, cell cycle evaluation and immunophenotyping. Their means to create a barrier was examined by TEER measurement and sodium fluorescein transport exercise.

Rat Caspase 3, Casp-3 ELISA Kit
1-CSB-E08857r	Cusabio	EUR 723.00 EUR 4883.00 EUR 2591.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase 3, Casp-3 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Caspase 3, Casp-3 ELISA Kit
CSB-E08858m-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase 3, Casp-3 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Caspase 3, Casp-3 ELISA Kit
1-CSB-E08858m	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase 3, Casp-3 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Caspase 3(Casp-3) ELISA Kit
CSB-E15965Rb-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rabbit Caspase 3 (Casp-3) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit Caspase 3(Casp-3) ELISA Kit
1-CSB-E15965Rb	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Caspase 3(Casp-3) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Caspase 3(Casp-3) ELISA Kit
CSB-E16274B-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 3 (Casp-3) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Bovine Caspase 3(Casp-3) ELISA Kit
1-CSB-E16274B	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 3(Casp-3) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Caspase 3,Casp-3 ELISA Kit
QY-E30325	Qayee Biotechnology	96T	EUR 374

Rat Caspase 3,Casp-3 ELISA Kit
QY-E11669	Qayee Biotechnology	96T	EUR 374

Mouse Caspase 3,Casp-3 ELISA Kit
CN-02588M1	ChemNorm	96T	EUR 439

Mouse Caspase 3,Casp-3 ELISA Kit
CN-02588M2	ChemNorm	48T	EUR 290

Rat Caspase 3,Casp-3 ELISA Kit
CN-01710R1	ChemNorm	96T	EUR 452

Rat Caspase 3,Casp-3 ELISA Kit
CN-01710R2	ChemNorm	48T	EUR 302

FSH (Human Follicle-stimulating hormone) ELISA test
3	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of FSH (Human Follicle-stimulating hormone)

Caspase-8 IETD-R110 Fluorometric HTS Assay Kit
30012-3	Biotium	1KIT	EUR 1627
Description: Minimum order quantity: 1 unit of 1KIT

IL-3 Interleukin-3 Human Recombinant Protein, His Tag
PROTP08700-3	BosterBio	Regular: 50ug	EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 154 amino acids fragment (20-152) and having a total molecular mass of 17.3kDa and fused with a 20 aa N-terminal His tag. ;The IL3 His is purified by proprietary chromatographic techniques.

Dr. P Kit-Solution 3
K2021010-3	Biochain	50 ml	EUR 133
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Anti-Caspase-8 Monoclonal Antibody (5F7)
M00042-3	BosterBio	100ug	EUR 420
Description: Mouse Monoclonal Caspase-8 Antibody (5F7). Validated in IP, IHC, WB and tested in Human.

Anti-Caspase-9 Rabbit Monoclonal Antibody
M00080-3	BosterBio	100ug/vial	EUR 397
Description: Rabbit Monoclonal Caspase-9 Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Caspase-8 Inhibitor, Q-IETD-OPh
1176-3	Biovision		EUR 686

Caspase-9 Inhibitor, Q-LEHD-OPh
1177-3	Biovision		EUR 675

Recombinant Human MMP-3 Protein
PROTP08254-3	BosterBio	10ug	EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant
PROTP10600-3	BosterBio	Regular: 5ug	EUR 317
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody
M02431-3	BosterBio	100ug/vial	EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

3-D Life Thioglycerol
T10-3	Cellendes	180 µl	EUR 48

Individual Reaction Mix 3
G065-3	ABM	200 reactions	EUR 167

Human Caspase-9, Casp-9 ELISA Kit
CSB-E08862h-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Caspase-9, Casp-9 ELISA Kit
1-CSB-E08862h	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Caspase 1(Casp-1) ELISA Kit
CSB-E13025h-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Caspase 1 (Casp-1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Caspase 1(Casp-1) ELISA Kit
1-CSB-E13025h	Cusabio	EUR 900.00 EUR 5476.00 EUR 2900.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Caspase 1(Casp-1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Caspase 8(Casp-8) ELISA Kit
CSB-E13636h-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Caspase 8 (Casp-8) in samples from serum, plasma, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Caspase 8(Casp-8) ELISA Kit
1-CSB-E13636h	Cusabio	EUR 900.00 EUR 5476.00 EUR 2900.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Caspase 8(Casp-8) in samples from serum, plasma, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Caspase 12,Casp-12 ELISA Kit
CN-03708H1	ChemNorm	96T	EUR 486

Human Caspase 12,Casp-12 ELISA Kit
CN-03708H2	ChemNorm	48T	EUR 336

Human Caspase-9,Casp-9 ELISA Kit
CN-03799H1	ChemNorm	96T	EUR 480

Human Caspase-9,Casp-9 ELISA Kit
CN-03799H2	ChemNorm	48T	EUR 331

Human Caspase 1(Casp 1) ELISA kit
E01C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 1(Casp 1) ELISA kit
E01C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Human Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 1(Casp 1) ELISA kit
E01C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Human Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9
PROTP49763-3	BosterBio	Regular: 25ug	EUR 317
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques.

Western Blot Box - 2 7/8 x 1 3/16 x 3/4in.; 7.3 x 3 x 1.9cm
B1200-3	MTC Bio	5/pack	EUR 63.77
Description: Western Blot Boxes

3-D-Life SG-PVA
M81-3	Cellendes	3x 170 µl	EUR 148

3-D Life FG-PVA
M82-3	Cellendes	3x 170 µl	EUR 148

3-D Life SG-Dextran
M91-3	Cellendes	3x 170 µl	EUR 157

3-D Life FG-Dextran
M92-3	Cellendes	3x 170 µl	EUR 157

3-D Life PEG-Link
L50-3	Cellendes	3x 200 µl	EUR 94

3-D Life CD-Link
L60-3	Cellendes	3 x 200 µl	EUR 321

3-D Life RGD Peptide
P10-3	Cellendes	3x 1 µmol	EUR 276

pLenti-CARM1 shRNA-3 Plasmid
PVTBAV03691-3	Lifescience Market	2 ug	EUR 356

pLenti-CTLA4 shRNA-3 Plasmid
PVTBAV05689-3	Lifescience Market	2 ug	EUR 356

pLenti-FOXM1 shRNA-3 Plasmid
PVTBAV08732-3	Lifescience Market	2 ug	EUR 356

pLenti-JUN shRNA-3 Plasmid
PVTBAV11741-3	Lifescience Market	2 ug	EUR 356

pLenti-LHX6 shRNA-3 Plasmid
PVTBAV12881-3	Lifescience Market	2 ug	EUR 356

pLenti-MAGEA3 shRNA-3 Plasmid
PVTBAV13661-3	Lifescience Market	2 ug	EUR 356

pLenti-RUNX3 shRNA-3 Plasmid
PVTBAV20583-3	Lifescience Market	2 ug	EUR 356

pLenti-Slc7a11 shRNA-3 Plasmid
PVTBAV21973-3	Lifescience Market	2 ug	EUR 356

pLenti-STAT3 shRNA-3 Plasmid
PVTBAV22921-3	Lifescience Market	2 ug	EUR 356

3-D Life Scrambled RGD Peptide
P11-3	Cellendes	3x 1 µmol	EUR 276

Anti-VEGF Receptor 3/FLT4 Antibody
A01276-3	BosterBio	100ug/vial	EUR 334

ANGPTL3 (17-460)Human Angiopoietin-like Protein 3 (17-460 a.a.) Human Recombinant Protein
PROTQ9Y5C1-3	BosterBio	Regular: 10ug	EUR 317
Description: ANGPTL3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 453 amino acids (17-460 a.a.) and having a molecular mass of 52.9kDa (Migrates at 25-70kDa on SDS-PAGE under reducing conditions).

Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12)
M00621-3	BosterBio	100ug/vial	EUR 334

Rabbit Complement 3-4 WK (100-mL)
31061-3	Pel-Freez	100mL	EUR 1102.48

QuantiMir 3'-Universal Primer (10,000 qPCR reactions)
RA420AU-3	SBI	10,000 assays	EUR 178

SeraMir 3'-Universal Primer (10,000 qPCR reactions)
RA800P-3	SBI	10,000 reactions	EUR 178

Anti-Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Monoclonal Antibody
M00227-3	BosterBio	100ul	EUR 397
Description: Mouse Monoclonal Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Antibody. Validated in IHC, WB and tested in Equine.

3-D Life 10x CB-Buffer (pH 5.5)
B10-3	Cellendes	600 µl	EUR 44

3-D Life 10x CB Buffer (pH 7.2)
B20-3	Cellendes	600 µL	EUR 44

ELISA kit for Human CASP 9 (Caspase 9)
E-EL-H0663	Elabscience Biotech	1 plate of 96 wells	EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human CASP 9 (Caspase 9) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Caspase-2, CASP-2
EK3742	SAB	96 tests	EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Caspase-2, CASP-2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Caspase-9, Casp-9 ELISA Kit
CSB-E08863r-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Caspase-9, Casp-9 ELISA Kit
1-CSB-E08863r	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Caspase-9, Casp-9 ELISA Kit
CSB-E08864m-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Caspase-9, Casp-9 ELISA Kit
1-CSB-E08864m	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Caspase-8, Casp-8 ELISA Kit
CSB-E14912r-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-8, Casp-8 in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Caspase-8, Casp-8 ELISA Kit
1-CSB-E14912r	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-8, Casp-8 in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Caspase 8(Casp-8) ELISA Kit
CSB-E17160B-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 8 (Casp-8) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Bovine Caspase 8(Casp-8) ELISA Kit
1-CSB-E17160B	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 8(Casp-8) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Caspase 7(Casp-7) ELISA Kit
CSB-E17315B-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 7 (Casp-7) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Bovine Caspase 7(Casp-7) ELISA Kit
1-CSB-E17315B	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Bovine Caspase 7(Casp-7) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Caspase 8(Casp-8) ELISA Kit
QY-E11898	Qayee Biotechnology	96T	EUR 374

Rat Caspase 9(Casp-9) ELISA Kit
QY-E11899	Qayee Biotechnology	96T	EUR 374

Mouse Caspase-9,Casp-9 ELISA Kit
CN-02586M1	ChemNorm	96T	EUR 438

Mouse Caspase-9,Casp-9 ELISA Kit
CN-02586M2	ChemNorm	48T	EUR 289

Rat Caspase-9,Casp-9 ELISA Kit
CN-01708R1	ChemNorm	96T	EUR 452

Rat Caspase-9,Casp-9 ELISA Kit
CN-01708R2	ChemNorm	48T	EUR 302

Rat Caspase 1(Casp 1) ELISA kit
E02C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caspase 1(Casp 1) ELISA kit
E02C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caspase 1(Casp 1) ELISA kit
E02C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 1(Casp 1) ELISA kit
E09C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 1(Casp 1) ELISA kit
E09C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 1(Casp 1) ELISA kit
E09C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 1(Casp 1) ELISA kit
E08C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 1(Casp 1) ELISA kit
E08C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 1(Casp 1) ELISA kit
E08C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caspase 1(Casp 1) ELISA kit
E04C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caspase 1(Casp 1) ELISA kit
E04C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caspase 1(Casp 1) ELISA kit
E04C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 1(Casp 1) ELISA kit
E03C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 1(Casp 1) ELISA kit
E03C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 1(Casp 1) ELISA kit
E03C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 1(Casp 1) ELISA kit
E07C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 1(Casp 1) ELISA kit
E07C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 1(Casp 1) ELISA kit
E07C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 1(Casp 1) ELISA kit
E06C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 1(Casp 1) ELISA kit
E06C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 1(Casp 1) ELISA kit
E06C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1030-3	Biovision		EUR 441

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1031-3	Biovision		EUR 436

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)
M1032-3	Biovision		EUR 436

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)
M1033-3	Biovision		EUR 436

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)
M1034-3	Biovision		EUR 332

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)
M1035-3	Biovision		EUR 430

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)
M1036-3	Biovision		EUR 430

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)
M1037-3	Biovision		EUR 430

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions)
M1039-3	Biovision		EUR 436

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
RD-CA15-3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 478

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
RD-CA15-3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 662

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
DLR-CA15-3-Hu-48T	DL Develop	48T	EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 15-3 (CA15-3) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
DLR-CA15-3-Hu-96T	DL Develop	96T	EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 15-3 (CA15-3) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
RDR-CA15-3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 500

Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
RDR-CA15-3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 692

Caspase-7 (CASP-7) Antibody
abx412064-01mg	Abbexa	0.1 mg	EUR 509

Caspase-7 (CASP-7) Antibody
abx412618-01mg	Abbexa	0.1 mg	EUR 509

Caspase-7 (CASP-7) Antibody
abx224115-100ug	Abbexa	100 ug	EUR 411

ELISA kit for Porcine CASP 9 (Caspase 9)
E-EL-P0612	Elabscience Biotech	1 plate of 96 wells	EUR 584
Description: A sandwich ELISA kit for quantitative measurement of Porcine CASP 9 (Caspase 9) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat Caspase-2, CASP-2
EK3743	SAB	96 tests	EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Caspase-2, CASP-2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Guinea pig Caspase 1(Casp 1) ELISA kit
E05C1391-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Caspase 1(Casp 1) ELISA kit
E05C1391-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Caspase 1(Casp 1) ELISA kit
E05C1391-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 1(Casp 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Anti-Human/Mouse Caspase-3 (ICE-3/LICE/Yama/CASP-3) antiserum #1
CASP31-S	Alpha Diagnostics	100 ul	EUR 457

CLIA kit for Human CASP 9 (Caspase 9)
E-CL-H0504	Elabscience Biotech	1 plate of 96 wells	EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human CASP 9 (Caspase 9) in samples from Serum, Plasma, Cell supernatant

Lethal factor Protease Substrate 3, AMC derivative MEk2 peptide substrate for high-throughput screening of LF inhibitors (14aa)
LFPS-3	Alpha Diagnostics	1 mg	EUR 408

Mouse anti-dsDNA IgG3-specific ELISA Kit, 96 tests, Quantitative
5120-3	Alpha Diagnostics	1 kit	EUR 712

Human Caspase-3 ELISA Kit
EHC0556	Abclonal	96Tests	EUR 521

Human Caspase 3 ELISA kit
E01C0549-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Caspase 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 3 ELISA kit
E01C0549-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Human Caspase 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 3 ELISA kit
E01C0549-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Human Caspase 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Caspase-3 (Human) ELISA Kit
K4221-100	Biovision		EUR 827

Papanicolaou (PAP) Stain Kit
PAP-3	ScyTek Laboratories	1000 ml ea.	EUR 200

Hematoxylin, Weigert's Iron Kit
HWI-3	ScyTek Laboratories	2000 ml	EUR 200

EZExtract? Polyubiquitin Buffer Kit
K6570-3	Biovision		EUR 240

RPS27A Human, Ubiquitin Biotinylated Human Recombinant Protein
PROTP62988-3	BosterBio	Regular: 10ug	EUR 317
Description: Recombinant Human RPS27A protein biotinylated with NHS-biotin produced in E.Coli is a single, non-glycosylated polypeptide chain containing a total of 76 amino acids and having a molecular mass of 8.6 kDa.

Human, Flt3 Ligand Human Recombinant Protein, His Tag
PROTP49771-3	BosterBio	Regular: 20ug	EUR 317
Description: Flt3-Ligand Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing 165 amino acids (including his tag) and having a molecular mass of 18.9 kDa. Flt3-Ligand is purified by proprietary chromatographic techniques.

IL17A Human, Interleukin 17A Human Recombinant Protein, Sf9
PROTQ16552-3	BosterBio	Regular: 10ug	EUR 317
Description: IL17A produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (24-155 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 138 amino acids and having a molecular mass of 15.9kDa.;IL17A shows multiple bands between 13.5-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

IL17F Human, Interleukin 17F Human Recombinant Protein, sf9
PROTQ96PD4-3	BosterBio	Regular: 5ug	EUR 317
Description: IL17F produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 142 amino acids (31-163 a.a.) and having a molecular mass of 16kDa (Molecular size on SDS-PAGE will appear at approximately 18-28 kDa). IL17F is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

IFNG Human, Interferon-gamma Human Recombinant Protein, HEK
PROTP01579-3	BosterBio	Regular: 25ug	EUR 317
Description: Interferon-gamma Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 16.8kDa due to glycosylation.;The IFNG is purified by proprietary chromatographic techniques.

OPG Human, Osteoprotegerin Human Recombinant Protein, Hi-5
PROTO00300-3	BosterBio	Regular: 10ug	EUR 317
Description: Recombinant Osteoprotegerin produced in baculovirus is a signle, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa. The Osteoprotegerin is fused to a 17 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

Myoglobin Human protein
PROTP02144-3	BosterBio	Regular: 1mg	EUR 577
Description: Human Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. ;Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.

Human Topoisomerase IIa
TG2000H-3	TopoGen	1000 units	EUR 705

Human recombinant UBE2D3
6430-3	Biovision		EUR 365

Human recombinant UBE2L3
6431-3	Biovision		EUR 365

LIGHT, Human Recombinant
P1291-3	Biovision		EUR 175

gAcrp30 Human, Globular Adiponectin Human Recombinant Protein, His Tag
PROTQ15848-3	BosterBio	Regular: 10ug	EUR 317
Description: Acrp30 Human has a total of 171 amino acids. N-terminal underlined amino acids are His-tag and the protease cleavage site (31AA-Underlined). The AA sequence of Acrp30 Human is homologous to the 105-244 amino acid sequence of the Human full-length Adiponectin (Swiss-prot entry Q15848).

OSM Human, Oncostatin M Human Recombinant Protein (209 a.a.)
PROTP13725-3	BosterBio	Regular: 10ug	EUR 317
Description: Oncostatin-M (209 a.a.) Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 209 amino acids and having a molecular mass of 23.9kDa. ;The Oncostatin-M (209 a.a.) is purified by proprietary chromatographic techniques.

LIF Human, Leukemia Inhibitory Factor Human Recombinant Protein, HEK
PROTP15018-3	BosterBio	Regular: 10ug	EUR 317
Description: Leukemia Inhibitory Factor Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 19.9kDa due to glycosylation.;The LIF is purified by proprietary chromatographic techniques.

Protein A IgG Purification Buffer Kit
K6529-3	Biovision		EUR 218

ACES™ YebF Protein Export Kit
0148-3	AthenaES	kit	EUR 311

TNFR Human, Tumor Necrosis Factor Receptor, sf9 Human Recombinant Protein
PROTQ07011-3	BosterBio	Regular: 10ug	EUR 317
Description: TNFR produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 411 amino acids (18-186 a.a.) and having a molecular mass of 45.3kDa. (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).

Recombinant Human TPO Protein
PROTP40225-3	BosterBio	10ug	EUR 317
Description: TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

Recombinant Human Leptin Protein
PROTP41159-3	BosterBio	1mg	EUR 317
Description: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant human Leptin is a 16.0 kDa protein containing 147 amino acid residues.

Recombinant Human Sox2 Protein
PROTP48431-3	BosterBio	25ug	EUR 317
Description: Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF-4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology, gene expression, and in the capacity to form teratomas in immune-deficient mice. Recombinant human Sox2 is a 34.3 kDa protein containing 317 amino-acid residues.

Recombinant Human NOGGIN Protein
PROTQ13253-3	BosterBio	20ug	EUR 317
Description: Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant human Noggin is a 46 kDa disulfide-linked homodimer (120-10C) consisting of two 206 amino acid polypeptide chains. Monomeric glycosylated Noggin migrates at an apparent molecular weight of approximately 28.0-33.0 kDa by SDS PAGE analysis under reducing conditions.

Recombinant Human Epigen Protein
PROTQ6UW88-3	BosterBio	25ug	EUR 317
Description: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.

Recombinant Human Chemerin Protein
PROTQ99969-3	BosterBio	25ug	EUR 317
Description: Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.

Recombinant Human Nanog Protein
PROTQ9H9S0-3	BosterBio	20ug	EUR 317
Description: Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self renewal via a STAT3 independent pathway. Recombinant human Nanog is a 34.5 kDa protein, which is synthesized as a 304 amino acid polypeptide lacking a signal sequence for secretion.

Recombinant Human Tigar Protein
PROTQ9NQ88-3	BosterBio	25ug	EUR 317
Description: TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant human TIGAR expressed in E. coli is a 29.9 kDa protein containing 269 amino-acid residues.

Recombinant Human AITRL Protein
PROTQ9UNG2-3	BosterBio	20ug	EUR 317
Description: AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.

Recombinant Human BAFF Protein
PROTQ9Y275-3	BosterBio	20ug	EUR 317
Description: BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.

Anti-Human Ki67 Antibody
M00254-3	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Human Ki67 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Human IBA1 Antibody
M01394-3	BosterBio	100ul	EUR 397
Description: Chicken Polyclonal Human IBA1 Antibody. Validated in IF, IHC, WB and tested in Human.

Recombinant Human ApoE3 Protein
PROTP02649-3	BosterBio	500ug	EUR 317
Description: ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human ApoE3 is a 34.0 kDa protein containing 299 amino acid residues.

Recombinant Human sCD14 Protein
PROTP08571-3	BosterBio	50ug	EUR 317
Description: CD14 is a cell surface anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor.

Recombinant Human Follistatin Protein
PROTP19883-3	BosterBio	20ug	EUR 317
Description: Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

Recombinant Human SCF Protein
PROTP21583-3	BosterBio	10ug	EUR 317
Description: Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Recombinant Human BDNF Protein
PROTP23560-3	BosterBio	10ug	EUR 317
Description: BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.

Recombinant Human CNTF Protein
PROTP26441-3	BosterBio	20ug	EUR 317
Description: CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.

Recombinant Human sCD34 Protein
PROTP28906-3	BosterBio	20ug	EUR 317
Description: CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein.

Recombinant Human CTGF Protein
PROTP29279-3	BosterBio	20ug	EUR 317
Description: CTGF is a member of the CCN family of secreted cysteine rich regulatory proteins and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial, and epithelial cells, and binds to IGF, TGF β1, and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Recombinant human CTGF is a 11.0 kDa protein of 97 amino acid residues.

Recombinant Human PEDF Protein
PROTP36955-3	BosterBio	20ug	EUR 317
Description: PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body. A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. In addition, PEDF is able to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins. The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. To date, PEDF-R is the only signaling receptor known to be used by a serpin family member. The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant PEDF is a 44.5 kDa non-glycosylated protein containing 400 amino acid residues. (1) Notari, I. et al. J Biol Chem., Vol. 281, 38022-38037.

Human CCL4 Recombinant Protein
R00703-3	BosterBio	5ug/vial	EUR 259
Description: The small chemotactic cytokine CCL4 (MIP-1 beta) is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is involved in several inflammatory and autoimmune diseases including viral infection such as HIV-1/AIDS. Human CCL4 Recombinant Protein is purified chemokine ligand 4 (CCL4, MIP-1 beta) produced in yeast.

Human CXCL9 Recombinant Protein
R01397-3	BosterBio	5ug/vial	EUR 259
Description: CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. Human CXCL9 Recombinant Protein is purified CXCL9 (MIG) produced in yeast.

Human TDP2 DNA Substrate
TG2038-3	TopoGen	50 ug	EUR 537

Human recombinant UBE2R1 (CDC34)
6436-3	Biovision		EUR 365

Human recombinant UBE2R2 (Ubc3B)
6437-3	Biovision		EUR 392

Human recombinant UBE2E2 (UbcH8)
6438-3	Biovision		EUR 392

sIL-4R?, Human Recombinant
P1287-3	Biovision		EUR 175

TIMP2 Human, Tissue Inhibitor of Metalloprotease 2 Human Recombinant Protein, Sf9
PROTP16035-3	BosterBio	Regular: 5ug	EUR 317
Description: TIMP2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 200 amino acids (27-220a.a.) and having a molecular mass of 22.5kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). TIMP2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CNMCS Compartmental Protein Extraction Kit: Buffer N
K3013010-3	Biochain	6 ml	EUR 114
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

TNFR2 Human, Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein, Sf9
PROTP20333-3	BosterBio	Regular: 10ug	EUR 317
Description: TNFR2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (23-257 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 241 amino acids and having a molecular mass of 25.9kDa.;TNFR2 shows multiple bands between 28-40kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Recombinant Human IL-15 Protein
PROTP40933-3	BosterBio	10ug	EUR 317
Description: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 12.9 kDa protein consisting of 114 amino acid residues.

Recombinant Human VEGF-C Protein
PROTP49767-3	BosterBio	20ug	EUR 317
Description: VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant human VEGF-C is a 13.5 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.

Recombinant Human sTRAIL/Apo2L Protein
PROTP50591-3	BosterBio	50ug	EUR 317
Description: TRAIL/Apo2L is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which activates the cell's apoptotic machinery. Recombinant human soluble TRAIL/Apo2L is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein.

Recombinant Human FGF-23 Protein
PROTQ9GZV9-3	BosterBio	20ug	EUR 317
Description: The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant human FGF-23 is a 22.5 kDa globular protein containing 228 amino acid residues.

Recombinant Human IL-17B Protein
PROTQ9UHF5-3	BosterBio	25ug	EUR 317
Description: IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-α and IL-1β from cells of the monocyte lineage. Recombinant human IL-17B is a 36.6 kDa non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.

Recombinant Human DKK-1 Protein
PROTO94907-3	BosterBio	10ug	EUR 317
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

Recombinant Human TIMP-1 Protein
PROTP01033-3	BosterBio	10ug	EUR 317
Description: TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.

Recombinant Human IFN-Beta Protein
PROTP01574-3	BosterBio	20ug	EUR 317
Description: Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFNβ. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNα contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNβ is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNβ has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry. *Human IFN-β(Catalog Number 300-02BC) has replaced Human IFN-β(Catalog Number 300-02B)

Recombinant Human MMP-1 Protein
PROTP03956-3	BosterBio	10ug	EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens. Recombinant human MMP-1 is a 42.7 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain which is involved in substrate specificity and in binding TIMP-1.

Recombinant Human ICAM-1 Protein
PROTP05362-3	BosterBio	50ug	EUR 317
Description: ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of approximately 72.0-80.0 kDa by SDS-PAGE analysis under reducing conditions.

Expression of 84 genes associated to drug transporters was evaluated by a PCR array. Our outcomes present that major cells specific epithelial cell markers: CKs, CK18, E-Cad and tight junctions molecules ZO-1 and OCL. All of the three pMEC mobile traces had been in a position to create a decent barrier, though with totally different strengths and kinetics, and specific the primary ABC and SLC drug transporters. In conclusion, within the current paper we’ve reported an environment friendly methodology to acquire major pMEC traces to review epithelial barrier operate within the pig mannequin.