Category: PCR

A Curious Novel Combination of Nucleophosmin ( NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML)

A Curious Novel Combination of Nucleophosmin ( NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML)A Curious Novel Combination of Nucleophosmin ( NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML)

Nucleophosmin (NPM1) mutations occurring in acute myeloid leukemia (AML) (about 50 up to now recognized) cluster nearly completely in exon 12 and result in frequent modifications on the NPM1 mutants C-terminus, i.e., lack

The Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia

The Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsiaThe Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia

Maternal cigarette smoking (CS) and pre-eclampsia (PE) alter placental operate and expression of vital proteins which preserve homeostasis. Two interlinked pathways of curiosity are the unfolded protein response (UPR) and

Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis

Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosisProtein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis

Macrophage-induced inflammation is a major factor in the pathogenesis of endometriosis. The underlying mechanisms, however, remain largely unknown. TNF-α, IL-6, IL-10 and C-C motif chemokine 20 (CCL20) levels in endometrial

C1q/TNF-related protein 9 decreases cardiomyocyte hypoxia/reoxygenation-induced inflammation by inhibiting the TLR4/MyD88/NF-κB signaling pathway

C1q/TNF-related protein 9 decreases cardiomyocyte hypoxia/reoxygenation-induced inflammation by inhibiting the TLR4/MyD88/NF-κB signaling pathwayC1q/TNF-related protein 9 decreases cardiomyocyte hypoxia/reoxygenation-induced inflammation by inhibiting the TLR4/MyD88/NF-κB signaling pathway

C1q/TNF-related protein 9 (CTRP9) acts as an adipokine and has been reported to exert quite a few organic features, comparable to anti-inflammatory and anti-oxidative stress results, in ischemic coronary heart

Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathwayOxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

Microglia are the first immune cells concerned within the immune response, irritation, and harm restore within the central nervous system. Beneath completely different stimuli, the twin polarization of classically-activated M1