Envelope protein-targeted vaccines for flaviviruses are restricted by considerations of antibody-dependent enhancement (ADE) of infections. Nonstructural protein 1 (NS1) supplies an alternate vaccine goal that avoids this danger since this
Category: Mucin 2 Antibody
Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniquesBispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniques
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Bispecific antibodies (bsAbs) are thought of as an essential class of biopharmaceutical medicine, with about 160 merchandise in scientific trials. From an analytical standpoint, the right chain-association is likely one
Combination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in WoodchucksCombination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in Woodchucks
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Present therapy choices for sufferers contaminated with hepatitis B virus (HBV) are suboptimal, as a result of the authorized medication hardly ever induce remedy as a result of persistence of
Development of purified glycogen derivatives as siRNA nanovectorsDevelopment of purified glycogen derivatives as siRNA nanovectors
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Purified Glycogen (PG) is a extremely hyper branched carbohydrate, characterised by excessive water solubility and really average enhance in viscosity. The dendrimeric construction of PG, appropriately functionalized, makes it an
Development of Human Toxo IgG ELISA Kit, and False-Positivity of Latex Agglutination Test for the Diagnosis of ToxoplasmosisDevelopment of Human Toxo IgG ELISA Kit, and False-Positivity of Latex Agglutination Test for the Diagnosis of Toxoplasmosis
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Toxoplasma gondii is an intracellular zoonotic parasite that causes an infection in a variety of warm-blooded animals and people. The principle purpose of this research was to evaluate the diagnostic worth
A Curious Novel Combination of Nucleophosmin ( NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML)A Curious Novel Combination of Nucleophosmin ( NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML)
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Nucleophosmin (NPM1) mutations occurring in acute myeloid leukemia (AML) (about 50 up to now recognized) cluster nearly completely in exon 12 and result in frequent modifications on the NPM1 mutants C-terminus, i.e., lack
The Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsiaThe Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia
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Maternal cigarette smoking (CS) and pre-eclampsia (PE) alter placental operate and expression of vital proteins which preserve homeostasis. Two interlinked pathways of curiosity are the unfolded protein response (UPR) and
Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosisProtein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis
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Macrophage-induced inflammation is a major factor in the pathogenesis of endometriosis. The underlying mechanisms, however, remain largely unknown. TNF-α, IL-6, IL-10 and C-C motif chemokine 20 (CCL20) levels in endometrial
Measurement of progesterone in sheep using a commercial ELISA kit for human plasmaMeasurement of progesterone in sheep using a commercial ELISA kit for human plasma
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Willpower of serum or plasma progesterone (P4) concentrations is necessary to acknowledge pregnant and non-pregnant ewes, and in addition to foretell the variety of carried lambs. The two most typical
Potential Protection of Pre-Existent Antibodies to Human Coronavirus 229E on COVID-19 SeverityPotential Protection of Pre-Existent Antibodies to Human Coronavirus 229E on COVID-19 Severity
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The causes of the broad spectrum of severity in COVID-19 are unknown. A protecting impact by humoral immunity from earlier infections by viruses of the SARS-CoV-2 household may clarify a