Development of purified glycogen derivatives as siRNA nanovectors

Purified Glycogen (PG) is a extremely hyper branched carbohydrate, characterised by excessive water solubility and really average enhance in viscosity. The dendrimeric construction of PG,

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The Unfolded Protein Response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia

Maternal cigarette smoking (CS) and pre-eclampsia (PE) alter placental operate and expression of vital proteins which preserve homeostasis. Two interlinked pathways of curiosity are the

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Maternal and neonatal canine cortisol measurement in multiple matrices during the perinatal period: A pilot study

Stress exposure during perinatal period may lead to maternal cortisol increase that negatively affects the offspring development. In recent years, the interest on non-invasive sampling

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Standardization and Evaluation of an Anti-ZIKV IgM ELISA Assay for the Serological Diagnosis of Zika Virus Infection

Here, we describe the development of the in-house anti-Zika virus (ZIKV) IgM antibody capture ELISA (in-house ZIKV IgM ELISA) for the detection and diagnosis of acute ZIKV infections.

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Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis

Macrophage-induced inflammation is a major factor in the pathogenesis of endometriosis. The underlying mechanisms, however, remain largely unknown. TNF-α, IL-6, IL-10 and C-C motif chemokine

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Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

Microglia are the first immune cells concerned within the immune response, irritation, and harm restore within the central nervous system. Beneath completely different stimuli, the

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Autoimmune anti-DNA and anti-phosphatidylserine antibodies predict development of severe COVID-19

Excessive ranges of autoimmune antibodies are noticed in COVID-19 sufferers however their particular contribution to illness severity and medical manifestations stays poorly understood. We carried

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Development of a nanobody-based competitive ELISA for efficiently and specifically detecting antibodies against genotype 2 porcine reproductive and respiratory syndrome viruses

Porcine reproductive and respiratory syndrome virus (PRRSV) an infection causes appreciable financial loss to the worldwide pig business. Environment friendly detection assay is essential for

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