Category: anti-Human

Epitope Mapping of the Anti-CD44 Monoclonal Antibody (C 44 Mab-46) Using Alanine-Scanning Mutagenesis and Surface Plasmon Resonance

Epitope Mapping of the Anti-CD44 Monoclonal Antibody (C 44 Mab-46) Using Alanine-Scanning Mutagenesis and Surface Plasmon ResonanceEpitope Mapping of the Anti-CD44 Monoclonal Antibody (C 44 Mab-46) Using Alanine-Scanning Mutagenesis and Surface Plasmon Resonance

CD44 is a kind I transmembrane protein expressed in varied sorts of regular most cancers cells, together with pancreatic, breast, and oral cancers. CD44 is related to most cancers development,

Mathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin ReceptorMathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin Receptor

We develop and analyze mathematical fashions for receptor-mediated transcytosis of monoclonal antibodies (MAb) focusing on the transferrin receptor (TfR) or the insulin receptor (IR), that are expressed on the blood-brain

Post-Vaccination Anti-SARS-CoV-2-Antibody Response in Patients with Multiple Myeloma Correlates with Low CD19+ B-Lymphocyte Count and Anti-CD38 Treatment

Post-Vaccination Anti-SARS-CoV-2-Antibody Response in Patients with Multiple Myeloma Correlates with Low CD19+ B-Lymphocyte Count and Anti-CD38 TreatmentPost-Vaccination Anti-SARS-CoV-2-Antibody Response in Patients with Multiple Myeloma Correlates with Low CD19+ B-Lymphocyte Count and Anti-CD38 Treatment

Few information can be found concerning the efficacy of anti-SARS-CoV-2 vaccines in sufferers with hematological malignancies, and specific, plasma cell neoplasia. This ongoing single-center examine aimed to explain the extent

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiationResting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Little is understood about how cells regulate and combine distinct biosynthetic pathways governing differentiation and cell division. For B-lineage cells it’s extensively accepted that activated cells should full a number

Fecal biomarkers of environmental enteric dysfunction and the gut microbiota of rural Malawian children: An observational study

Fecal biomarkers of environmental enteric dysfunction and the gut microbiota of rural Malawian children: An observational studyFecal biomarkers of environmental enteric dysfunction and the gut microbiota of rural Malawian children: An observational study

Environmental enteric dysfunction (EED) is a subclinical situation of the intestine characterised by adjustments in morphology and performance with underlying persistent inflammatory responses. This examine characterised composition and variety of

Fully human recombinant antibodies against EphA2 from a multi-tumor patient immune library suitable for tumor-targeted therapyFully human recombinant antibodies against EphA2 from a multi-tumor patient immune library suitable for tumor-targeted therapy

Enhanced EphA2 expression is noticed in a wide range of epithelial-derived malignancies and is a crucial goal for anti-tumor remedy. At the moment, Therapeutic monoclonal antibodies towards immune checkpoints have proven good efficacy for