Autoimmune anti-DNA and anti-phosphatidylserine antibodies predict development of severe COVID-19

| GregoryGregory | 0 Comment
Autoimmune anti-DNA and anti-phosphatidylserine antibodies predict development of severe COVID-19
Excessive ranges of autoimmune antibodies are noticed in COVID-19 sufferers however their particular contribution to illness severity and medical manifestations stays poorly understood. We carried out a retrospective research of 115 COVID-19 hospitalized sufferers with totally different levels of severity to research the technology of autoimmune antibodies to frequent antigens: a lysate of erythrocytes, the lipid phosphatidylserine (PS) and DNA.
Excessive ranges of IgG autoantibodies towards erythrocyte lysates have been noticed in a big proportion (as much as 36%) of sufferers. Anti-DNA and anti-PS antibodies decided upon hospital admission correlated strongly with later growth of extreme illness, exhibiting a constructive predictive worth of 85.7% and 92.8%, respectively. Sufferers with constructive values for not less than one of many two autoantibodies accounted for 24% of complete extreme instances.
Statistical evaluation recognized robust correlations between anti-DNA antibodies and markers of cell damage, coagulation, neutrophil ranges and erythrocyte dimension. Anti-DNA and anti-PS autoantibodies might play an essential position within the pathogenesis of COVID-19 and could possibly be developed as predictive biomarkers for illness severity and particular medical manifestations.

Anti-TRBC1 Antibody-Based mostly Circulate Cytometric Detection of T-Cell Clonality: Standardization of Pattern Preparation and Diagnostic Implementation

A single antibody (anti-TRBC1; JOVI-1 antibody clone) towards one of many two mutually unique T-cell receptor β-chain fixed domains was recognized as a probably helpful flow-cytometry (FCM) marker to evaluate Tαβ-cell clonality. We optimized the TRBC1-FCM method for detecting clonal Tαβ-cells and validated the tactic in 211 regular, reactive and pathological samples.
TRBC1 labeling considerably improved within the presence of CD3. Purified TRBC1+ and TRBC1– monoclonal and polyclonal Tαβ-cells rearranged TRBJ1 in 44/47 (94%) and TRBJ1+TRBJ2 in 48 of 48 (100%) populations, respectively, which confirmed the excessive specificity of this assay.
Moreover, TRBC1+/TRBC1– ratios inside totally different Tαβ-cell subsets are supplied as reference for polyclonal cells, amongst which a bimodal sample of TRBC1-expression profile was discovered for all TCRVβ households, whereas highly-variable TRBC1+/TRBC1– ratios have been noticed in additional mature vs. naïve Tαβ-cell subsets (vs. complete T-cells). In 112/117 (96%) samples containing clonal Tαβ-cells through which the method was validated, monotypic expression of TRBC1 was confirmed.
Dilutional experiments confirmed a stage of detection for detecting clonal Tαβ-cells of ≤10-4 in seven out of eight pathological samples. These outcomes help implementation of the optimized TRBC1-FCM method as a quick, particular and correct technique for assessing T-cell clonality in diagnostic-FCM panels, and for minimal (residual) illness detection in mature Tαβ+ leukemia/lymphoma sufferers.

IgG antibodies reacting with ghrelin and leptin are correlated with physique composition and appetitive traits in younger topics

Appetitive traits are essential behavioural traits affecting consuming and physique composition. Ghrelin and leptin are two key hormones regulating urge for food and metabolism. Current research have reported the presence of autoantibodies (autoAbs) directed to ghrelin and leptin in wholesome people in addition to affinity alterations in consuming problems resembling anorexia nervosa and hyperphagic weight problems. Nonetheless, the connection of those autoAbs with appetitive traits is unknown.
The targets of this exploratory research have been to research circulating IgG autoAbs reacting to ghrelin and leptin and consider their relationship with physique composition parameters and appetitive traits. This cross-sectional research included 180 younger topics (20 ± 2 years) that underwent physique composition analysis. Seven appetitive traits have been assessed with AEBQ-Esp and have been categorized as low-score or high-score.
A validated in-house ELISA take a look at was carried out to measure IgG ghrelin and leptin-reactive autoAbs in its free, complete, and immune complexes fractions. Free IgG ghrelin-reactive have been considerably greater in ladies than in males. Immune complexes of IgG-ghrelin have been positively correlated with waist-hip ratio within the complete cohort.
In ladies, free IgG leptin-reactive have been positively correlated with physique fats proportion and waist-hip ratio, whereas in males, immune complexes of IgG-leptin have been positively correlated with physique fats proportion.
Ladies with a low-score for ‘enjoyment of meals’, exhibited greater ranges of IgG ghrelin-reactive autoAbs on its free kind than the high-score group. Males with a high-score for ’emotional undereating’ had greater ranges of free IgG leptin-reactive autoAbs than the low-score group.
The correlation of those autoAbs with anthropometric parameters and appetitive traits in younger topics help its position as carriers and modulators of the biologic features of ghrelin and leptin and counsel a novel position in consuming behaviour by means of appetitive traits.

Validation of a Triplex Pharmacokinetic Assay for Simultaneous Quantitation of HIV-1 Broadly Neutralizing Antibodies PGT121, PGDM1400, and VRC07-523-LS

The result of the latest Antibody Mediated Prevention (AMP) trials that examined infusion of the broadly neutralizing antibody (bnAb) VRC01 offers proof of idea for blocking an infection from delicate HIV-1 strains. These outcomes additionally open up the chance that triple mixtures of bnAbs resembling PGT121, PGDM1400, in addition to long-lasting LS variants resembling VRC07-523 LS, have immunoprophylactic potential.
PGT121 and PGDM1400 goal the HIV-1 V3 and V2 glycan areas of the gp120 envelope protein, respectively, whereas VRC07-523LS targets the HIV-1 CD4 binding website. These bnAbs show neutralization efficiency and complementary breadth of HIV-1 pressure protection.
An essential medical trial final result is the correct measurement of in vivo concentrations of passively infused bnAbs to find out efficient doses for remedy and/or prevention. Standardization and validation of this testing technique is a key ingredient for medical research as is the power to concurrently detect a number of bnAbs in a selected method.
Right here we report the event of a delicate, particular, correct, and exact multiplexed microsphere-based assay that concurrently quantifies the respective physiological concentrations of passively infused bnAbs in human serum to in the end outline the brink wanted for defense from HIV-1 an infection.

Miniaturized single-cell applied sciences for monoclonal antibody discovery

Antibodies (Abs) are among the many most essential class of biologicals, showcasing a excessive therapeutic and diagnostic worth. Within the world therapeutic Ab market, fully-human monoclonal Abs (FH-mAbs) are flourishing because of their low immunogenicity and excessive specificity.
The quickly rising discipline of single-cell applied sciences has paved the best way to effectively uncover mAbs by facilitating a quick screening of the antigen (Ag)-specificity and performance of Abs expressed by B cells. This evaluation summarizes the rules and challenges of the 4 key ideas to find mAbs utilizing these applied sciences, being confinement of single cells utilizing both droplet microfluidics or microstructure arrays, identification of the cells of curiosity, retrieval of these cells and single-cell sequence willpower required for mAb manufacturing.

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC611130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF660R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC811130-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF680R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC811130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF680R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCP1130-250 250uL
EUR 459.6
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), PerCP conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCR1130-250 250uL
EUR 459.6
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), RPE conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCAP1130-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCAP1130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCH1130-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNCH1130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC431130-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF543 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC431130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF543 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC051130-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF405M conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(MUC18/1130) Antibody
BNC051130-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(MUC18/1130), CF405M conjugate, Concentration: 0.1mg/mL

MUC18/ CD146
MBS438396-002mgWithBSAAzideat02mgmL 0.02mg(WithBSA&Azideat0.2mg/mL)
EUR 230

MUC18/ CD146
MBS438396-01mgWithBSAAzideat02mgmL 0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 405

MUC18/ CD146
MBS438396-01mgWithoutBSAAzideat1mgmL 0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 405

MUC18/ CD146
MBS438396-5x01mgWithBSAAzideat02mgmL 5x0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 1725

MUC18/ CD146
MBS438396-5x01mgWithoutBSAAzideat1mgmL 5x0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 1725

MUC18 / Mucin 18 / CD146(MUC18/1130), 1mg/mL
BNUM1130-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), 0.2mg/mL
BNUB1130-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), 0.2mg/mL
BNUB1130-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF568 conjugate, 0.1mg/mL
BNC681130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF568 conjugate, 0.1mg/mL
BNC681130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF594 conjugate, 0.1mg/mL
BNC941130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF594 conjugate, 0.1mg/mL
BNC941130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF647 conjugate, 0.1mg/mL
BNC471130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF647 conjugate, 0.1mg/mL
BNC471130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF488A conjugate, 0.1mg/mL
BNC881130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF488A conjugate, 0.1mg/mL
BNC881130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), Biotin conjugate, 0.1mg/mL
BNCB1130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), Biotin conjugate, 0.1mg/mL
BNCB1130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF640R conjugate, 0.1mg/mL
BNC401130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF640R conjugate, 0.1mg/mL
BNC401130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF405S conjugate, 0.1mg/mL
BNC041130-100 100uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(MUC18/1130), CF405S conjugate, 0.1mg/mL
BNC041130-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146; Clone MUC18/1130 (Concentrate)
RA0444-C.1 0.1 ml
EUR 60.07

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146; Clone MUC18/1130 (Concentrate)
RA0444-C.5 0.5 ml
EUR 200.66

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146; Clone MUC18/1130 (Concentrate)
RA0444-C1 1 ml
EUR 361.66

Anti-MUC18/ CD146/ MCAM Antibody Clone MUC18/1130, Unconjugated-100ug
4162-MSM4-P1 100ug
EUR 513.6

Anti CD146/MUC18 (c3.19.1)
E40YR1641 1 mg
EUR 2960
Description: Available in various conjugation types.

CD146/MUC18/Mel-CAM
MBS370354-01mLConcentrate 0.1mL(Concentrate)
EUR 220

CD146/MUC18/Mel-CAM
MBS370354-05mLConcentrate 0.5mL(Concentrate)
EUR 435

CD146/MUC18/Mel-CAM
MBS370354-1mLConcentrate 1mL(Concentrate)
EUR 650

CD146/MUC18/Mel-CAM
MBS370354-3mLRTU 3mL(RTU)
EUR 285

CD146/MUC18/Mel-CAM
MBS370354-7mLRTU 7mL(RTU)
EUR 415

Cell surface glycoprotein MUC18
AP85760 1mg
EUR 2640

Cell surface glycoprotein MUC18
AP85545 1mg
EUR 2640

Cell surface glycoprotein MUC18
AP86009 1mg
EUR 2640

Cell surface glycoprotein MUC18
MBS7043076-001mg 0.01mg
EUR 1440

Cell surface glycoprotein MUC18
MBS7043076-005mg 0.05mg
EUR 1995

Cell surface glycoprotein MUC18
MBS7043076-01mg 0.1mg
EUR 2925

Monoclonal MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody, Clone: MUC18/1130
AMM01013G 7 ml
EUR 580.8
Description: A Monoclonal antibody against Human MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule). The antibodies are raised in Mouse and are from clone MUC18/1130. This antibody is applicable in IHC, IF, FC

Human MUC18 Protein, His Tag
MBS189070-001mg 0.01mg
EUR 225

Human MUC18 Protein, His Tag
MBS189070-005mg 0.05mg
EUR 410

Human MUC18 Protein, His Tag
MBS189070-5x005mg 5x0.05mg
EUR 1560

Anti-MCAM / CD146/ MUC18 antibody
STJ73585 100 µg
EUR 430.8

Cell surface glycoprotein MUC18 Antibody
20-abx109638
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  • 20 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

Cell Surface Glycoprotein MUC18 Antibody
MBS5400534-01mg 0.1mg
EUR 445

Cell Surface Glycoprotein MUC18 Antibody
MBS5400534-5x01mg 5x0.1mg
EUR 1855

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC700676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF770 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC700676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF770 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC800676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF680 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC800676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF680 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCA0676-250 250uL
EUR 459.6
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), APC conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC610676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF660R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC610676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF660R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC810676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF680R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC810676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF680R conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCH0676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCH0676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCP0676-250 250uL
EUR 459.6
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), PerCP conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCR0676-250 250uL
EUR 459.6
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), RPE conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCAP0676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNCAP0676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC430676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF543 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC430676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF543 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC050676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF405M conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC050676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF405M conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC550676-100 100uL
EUR 238.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF555 conjugate, Concentration: 0.1mg/mL

MUC18 / Mucin 18 / CD146(OJ79c) Antibody
BNC550676-500 500uL
EUR 652.8
Description: Primary antibody against MUC18 / Mucin 18 / CD146(OJ79c), CF555 conjugate, Concentration: 0.1mg/mL

Goat anti-MCAM / CD146/ MUC18 Antibody
dAP-3480 50ug
EUR 264.6

Goat anti-MCAM/CD146/ MUC18 Antibody
MBS423828-01mg 0.1mg
EUR 400

Goat anti-MCAM/CD146/ MUC18 Antibody
MBS423828-5x01mg 5x0.1mg
EUR 1660

Monoclonal MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody - With BSA and Azide, Clone: MUC18/1130
AMM01014G 0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) - With BSA and Azide. The antibodies are raised in Mouse and are from clone MUC18/1130. This antibody is applicable in IHC, IF, FC

Monoclonal MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody - Without BSA and Azide, Clone: MUC18/1130
AMM01015G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone MUC18/1130. This antibody is applicable in IHC, IF, FC

MUC18 / Mucin 18 / CD146(OJ79c), 0.2mg/mL
BNUB0676-100 100uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(OJ79c), 0.2mg/mL
BNUB0676-500 500uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MUC18 / Mucin 18 / CD146(OJ79c), 1mg/mL
BNUM0676-50 50uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Human Cell surface glycoprotein MUC18 (MCAM)
1-CSB-RP104394h
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  • 10ug
  • 50ug
  • 100ug
  • 200ug
  • 500ug
  • 1MG
Description: Recombinant Human Cell surface glycoprotein MUC18(MCAM),partial expressed in E.coli

Cell surface glycoprotein MUC18 Antibody (HRP)
20-abx108086
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  • 20 ug
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  • 1 mg

Cell surface glycoprotein MUC18 Antibody (FITC)
20-abx106669
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  • 20 ug
  • 50 ug
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  • 200 ug
  • 1 mg

Cell Surface Glycoprotein MUC18 (MCAM) Antibody
abx433582-100g 100 µg
EUR 387.5

Cell Surface Glycoprotein MUC18 Antibody FITC
MBS5400536-01mg 0.1mg
EUR 560

Cell Surface Glycoprotein MUC18 Antibody FITC
MBS5400536-5x01mg 5x0.1mg
EUR 2380

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx019043-100ug 100 ug
EUR 410.4

Cell surface glycoprotein MUC18 (CD146) Antibody
abx341056-100l 100 µl
EUR 400

Cell surface glycoprotein MUC18 (CD146) Antibody
abx341056-50l 50 µl
EUR 287.5

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx139732-01mg 0.1 mg
EUR 427.2

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx413746-02mg 0.2 mg
EUR 678

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx413749-25ug 25 ug
EUR 326.4

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx413750-1mg 1 mg
EUR 994.8

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx200495-100ug 100 ug
EUR 393.6

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx231428-100ug 100 ug
EUR 577.2

Cell Surface Glycoprotein MUC18 (CD146) Antibody
abx231429-100ug 100 ug
EUR 661.2

Cell Surface Glycoprotein MUC18 (CD146) Antibody
20-abx225287
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  • 50 ul
  • 100 ul
  • 200 ul

Cell surface glycoprotein MUC18 Antibody (Biotin)
20-abx105251
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  • 20 ug
  • 50 ug
  • 100 ug
  • 200 ug
  • 1 mg

Cell Surface Glycoprotein MUC18 Antibody BIOTIN
MBS5400535-01mg 0.1mg
EUR 560

Cell Surface Glycoprotein MUC18 Antibody BIOTIN
MBS5400535-5x01mg 5x0.1mg
EUR 2380

Cell Surface Glycoprotein MUC18 Blocking Peptide
MBS5400634-025mg 0.25mg
EUR 280

Cell Surface Glycoprotein MUC18 Blocking Peptide
MBS5400634-5x025mg 5x0.25mg
EUR 1110

Cell Surface Glycoprotein MUC18 Positive Control
MBS5400731-5Applications 5Applications
EUR 335

Cell Surface Glycoprotein MUC18 Positive Control
MBS5400731-5x5Applications 5x5Applications
EUR 1350

Recombinant Human Cell surface glycoprotein MUC18
MBS1265398-002mg 0.02mg
EUR 255

Recombinant Human Cell surface glycoprotein MUC18
MBS1265398-01mg 0.1mg
EUR 405

Recombinant Human Cell surface glycoprotein MUC18
MBS1265398-1mg 1mg
EUR 1425

Recombinant Human Cell surface glycoprotein MUC18
MBS1265398-5x1mg 5x1mg
EUR 6215

Recombinant Human Cell surface glycoprotein MUC18
MBS9421894-002mg 0.02mg
EUR 285

Recombinant Human Cell surface glycoprotein MUC18
MBS9421894-01mg 0.1mg
EUR 470

Recombinant Human Cell surface glycoprotein MUC18
MBS9421894-1mg 1mg
EUR 1785

Recombinant Human Cell surface glycoprotein MUC18
MBS9421894-5x1mg 5x1mg
EUR 7885

Cell surface glycoprotein MUC18 Polyclonal Antibody
42523 100μg
EUR 390

Cell surface glycoprotein MUC18 Polyclonal Antibody
42523-100ul 100ul
EUR 399.6

Cell surface glycoprotein MUC18 Polyclonal Antibody
MBS9415073-01mg 0.1mg
EUR 350

Cell surface glycoprotein MUC18 Polyclonal Antibody
MBS9415073-5x01mg 5x0.1mg
EUR 1420

PE anti-human CD146 (MUC18, Mel-CAM)
E16FHP146M-025 25 tests
EUR 455
Description: Available in various conjugation types.

PE anti-human CD146 (MUC18, Mel-CAM)
E16FHP146M-100 100 tests
EUR 975
Description: Available in various conjugation types.

APC anti-human CD146 (MUC18, Mel-CAM)
E16FHA146M-025 25 tests
EUR 541.67
Description: Available in various conjugation types.

APC anti-human CD146 (MUC18, Mel-CAM)
E16FHA146M-100 100 tests
EUR 1148.33
Description: Available in various conjugation types.

Purified anti-human CD146 (MUC18, Mel-CAM)
E16FHU146M-025U 25 μg
EUR 238.33
Description: Available in various conjugation types.

Purified anti-human CD146 (MUC18, Mel-CAM)
E16FHU146M-100U 100 μg
EUR 433.33
Description: Available in various conjugation types.

Rat Cell surface glycoprotein MUC18 ELISA Kit
EK3861 96 tests
EUR 599

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS2884111-10x96StripWells 10x96-Strip-Wells
EUR 4080

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS2884111-48StripWells 48-Strip-Wells
EUR 390

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS2884111-5x96StripWells 5x96-Strip-Wells
EUR 2220

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS2884111-96StripWells 96-Strip-Wells
EUR 520

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS9427691-5x96Tests 5x96Tests
EUR 2820

Rat Cell surface glycoprotein MUC18 ELISA Kit
MBS9427691-96Tests 96Tests
EUR 615

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC700634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF770 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC700634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF770 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC701101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF770 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC701101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF770 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC800634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF680 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC800634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF680 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC801101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF680 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC801101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF680 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC810634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF680R conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC810634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF680R conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCA0634-250 250uL
EUR 459.6
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), APC conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCA1101-250 250uL
EUR 459.6
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), APC conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC610634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF660R conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC610634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF660R conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC611101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF660R conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC611101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF660R conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC811101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF680R conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC811101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF680R conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCH0634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCH0634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCP0634-250 250uL
EUR 459.6
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), PerCP conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCP1101-250 250uL
EUR 459.6
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), PerCP conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCR0634-250 250uL
EUR 459.6
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), RPE conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCR1101-250 250uL
EUR 459.6
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), RPE conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCAP1101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCAP1101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCH1101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNCH1101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCAP0634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNCAP0634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC430634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF543 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC430634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF543 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC431101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF543 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC431101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF543 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC050634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF405M conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC050634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF405M conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC051101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF405M conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC051101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF405M conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC550634-100 100uL
EUR 238.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF555 conjugate, Concentration: 0.1mg/mL

CD146 / MCAM / MUC18 / Mucin 18(C146/634) Antibody
BNC550634-500 500uL
EUR 652.8
Description: Primary antibody against CD146 / MCAM / MUC18 / Mucin 18(C146/634), CF555 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC551101-100 100uL
EUR 238.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF555 conjugate, Concentration: 0.1mg/mL

MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101) Antibody
BNC551101-500 500uL
EUR 652.8
Description: Primary antibody against MCAM / MUC18 / Mucin 18 / CD146(MCAM/1101), CF555 conjugate, Concentration: 0.1mg/mL

Human Cell surface glycoprotein MUC18 ELISA Kit
EK3860 96 tests
EUR 599

Mouse Cell surface glycoprotein MUC18 ELISA Kit
MBS2883694-10x96StripWells 10x96-Strip-Wells
EUR 4080

Mouse Cell surface glycoprotein MUC18 ELISA Kit
MBS2883694-48StripWells 48-Strip-Wells
EUR 390

Mouse Cell surface glycoprotein MUC18 ELISA Kit
MBS2883694-5x96StripWells 5x96-Strip-Wells
EUR 2220

Mouse Cell surface glycoprotein MUC18 ELISA Kit
MBS2883694-96StripWells 96-Strip-Wells
EUR 520

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS2880042-10x96StripWells 10x96-Strip-Wells
EUR 4080

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS2880042-48StripWells 48-Strip-Wells
EUR 390

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS2880042-5x96StripWells 5x96-Strip-Wells
EUR 2220

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS2880042-96StripWells 96-Strip-Wells
EUR 520

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS762242-10x96StripWells 10x96-Strip-Wells
EUR 3900

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS762242-48StripWells 48-Strip-Wells
EUR 340

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS762242-5x96StripWells 5x96-Strip-Wells
EUR 2045

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS762242-96StripWells 96-Strip-Wells
EUR 455

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS9427690-5x96Tests 5x96Tests
EUR 2820

Human Cell surface glycoprotein MUC18 ELISA Kit
MBS9427690-96Tests 96Tests
EUR 615

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381077-002mgWithBSAAzideat02mgmL 0.02mg(WithBSA&Azideat0.2mg/mL)
EUR 230

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381077-01mgWithBSAAzideat02mgmL 0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 405

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381077-01mgWithoutBSAAzideat1mgmL 0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 405

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381077-5x01mgWithBSAAzideat02mgmL 5x0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 1725

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381077-5x01mgWithoutBSAAzideat1mgmL 5x0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 1725

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381078-002mgWithBSAAzideat02mgmL 0.02mg(WithBSA&Azideat0.2mg/mL)
EUR 230

MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146
MBS4381078-01mgWithBSAAzideat02mgmL 0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 405
This evaluation reveals the big potential for mix-and-matching of the above-mentioned methods, which is illustrated by the plethora of established, extremely built-in gadgets. Lastly, an outlook is given on the various alternatives and challenges that also lie forward to totally exploit miniaturized single-cell applied sciences for mAb discovery.
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