A survey of pharmacokinetic bioanalytical methods in biosimilar biological license applications (BLAs) for the assessment of target and antidrug antibodies effects

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A survey of pharmacokinetic bioanalytical methods in biosimilar biological license applications (BLAs) for the assessment of target and antidrug antibodies effects
The presence of circulating targets and antidrug antibodies can affect the power of a bioanalytical methodology to measure therapeutic protein (TP) focus related to exposure-response evaluations. This mission surveyed biosimilar submissions for his or her bioanalytical strategies. Survey outcomes revealed that 97% of pharmacokinetic strategies designed to measure theoretically free or partial-free TPs with respect to focus on certainly measured free or partial-free TPs when contemplating experimental testing outcomes for goal results.
Antidrug antibody impact is much less typically evaluated. The noticed development of measuring biologically lively types of TP is per the scientific understanding that pharmacokinetics of biologically lively kinds is extra more likely to be related to the medical responses and analysis of clinically significant variations to contribute to biosimilarity assessments.

Medical Options of Coexisting Anti-NMDAR and MOG Antibody-Related Encephalitis: A Systematic Evaluation and Meta-Evaluation

Coexisting anti-NMDAR and MOG antibody (anti-NMDAR-IgG+/MOG-IgG+)-associated encephalitis have garnered nice consideration. This research aimed to carry out a secondary evaluation to find out the medical options of this illness. We searched a number of databases for associated publications printed previous to April 2021. A pooled evaluation was carried out with the fixed-effects mannequin utilizing the Mante-Haenszel methodology (I 2 ≤ 50%), or the random-effects mannequin computed by the DerSimonian-Laird methodology (I 2 > 50%).
Stata software program (model 15.Zero SE) was used for the analyses. 9 observational research and 16 case stories (58 circumstances with anti-NMDAR-IgG+/MOG-IgG+, 21.0 [8.5, 29.0] years, male 58.6%) have been included. The incidences (95%CI) of anti-NMDAR-IgG+/MOG-IgG+ within the sufferers with serum MOG-IgG+ and CSF anti-NMDAR-IgG+ have been 0.09 (0.02-0.19) and 0.07 (0.01-0.19), respectively.
The median [IQR] of CSF anti-NMDAR antibody titer was 32 [10, 100], and the serum anti-MOG antibody titer was 100 [32, 320]. The distinguished medical signs have been encephalitic manifestations, together with seizures (56.9%) and irregular habits (51.7%), fairly than demyelinating manifestations, similar to speech dysfunction (34.5%) and optic neuritis (27.6%).
Relapse occurred in 63.4% of anti-NMDAR-IgG+/MOG-IgG+ sufferers, in whom 50.0% of circumstances relapsed with encephalitic manifestations, and 53.8% relapsed with demyelinating manifestations. The widespread MRI adjustments have been within the cortex or subcortex (70.7%) and brainstem (31.0%). 31.3% of sufferers introduced with unilateral cerebral cortical encephalitis with epilepsy and 12.5% displayed bilateral frontal cerebral cortex encephalitis.
Anti-NMDAR-IgG+/MOG-IgG+ sufferers confirmed extra frequent psychological habits (OR, 95%CI, 68.38, 1.36-3,434.37), involuntary motion (57.86, 2.53-1,325.11), sleep issues (195.00, 7.07-5,380.15), and leptomeninge lesions (7.32, 1.81-29.58), and fewer frequent optic neuritis (0.27, 0.09-0.83) in comparison with anti-NMDAR-IgG–/MOG-IgG+ sufferers and introduced extra widespread relapse (5.63, 1.75-18.09), previous an infection (2.69, 1.03-7.02), subcortical lesions (116.60, 4.89-2,782.09), basal ganglia lesions (68.14, 2.99-1,554.27), brainstem lesions (24.09, 1.01-574.81), and spinal twine lesions (24.09, 1.01-574.81) in comparison with anti-NMDAR-IgG+/MOG-IgG–. In conclusion, anti-NMDAR-IgG+/MOG-IgG+ was not often noticed, however the incidence price of relapse was very excessive. The general signs gave the impression to be much like these of NMDAR encephalitis.
A survey of pharmacokinetic bioanalytical methods in biosimilar biological license applications (BLAs) for the assessment of target and antidrug antibodies effects

Strategies to Determine Immunogenic Peptides in SARS-CoV-2 Spike and Protecting Monoclonal Antibodies in COVID-19 Sufferers

The extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) an infection and the related COVID-19 illnesses are an rising risk to international public well being. Though appreciable scientific analysis on the immune, particularly antibody, responses to SARS-CoV-2 an infection have been carried out, further dominant epitopes and protecting antibodies are wanted for prognosis and remedy of COVID-19 sufferers.
Right here, two completely different phage libraries are used to establish immunogenic epitopes throughout the spike protein and monoclonal antibodies from COVID-19 sufferers. Three peptides are additional characterised within the receptor-binding motif (RBM) and measured their antibody ranges in COVID-19 sufferers, from which one identifies one most immunodominant epitope with the best antibody response in COVID-19 sufferers and in immunized mice.
Extra importantly, monoclonal antibodies particularly binding to this peptide remoted from COVID-19 sufferers have therapeutic potential to neutralize SARS-CoV-2 an infection. Thus, the approaches to systemically establish immunogenic peptides and immediately establish human monoclonal antibodies from sufferers will present helpful diagnostic and therapeutic instruments for COVID-19 and different rising infectious illnesses.
A survey of pharmacokinetic bioanalytical methods in biosimilar biological license applications (BLAs) for the assessment of target and antidrug antibodies effects

Inhabitants pharmacokinetics and pharmacodynamics of the neutralizing antibodies bamlanivimab and etesevimab in sufferers with delicate to average COVID-19 an infection

Bamlanivimab and etesevimab are neutralizing antibodies indicated for remedy of COVID-19 in sufferers with early delicate or average illness. We current using pharmacokinetic-pharmacodynamic (PK/PD) modeling that characterizes the timecourse of viral load obtained from 2970 sufferers from two section 2 medical trials. The mannequin was used for identification of optimum doses that may end in not less than 90% of sufferers reaching serum drug concentrations that ends in 90% of most drug impact (IC90) for not less than 28 days.
The serum IC90 (95% confidence interval) was estimated to be 4.2 (3.2, 4.3) µg/mL for bamlanivimab and 12.6 (9.7, 12.8) µg/mL for etesevimab. Noticed medical trial knowledge confirmed PK and PK/PD mannequin predictions that doses of 700 mg bamlanivimab and 1400 mg etesevimab would end in most discount in viral load, with no further impact seen at increased doses.
No dose adjustment is really helpful as age, intercourse, race, baseline viral load and hepatic impairment didn’t have a big influence on the PK of the antibodies. Earlier drug administration resulted in higher reductions in viral load, demonstrating the significance of receiving remedy as quickly as potential.
Relative to placebo, typical discount in viral load over a 7 day interval was estimated to be 80 or 93% (drug administered Four days or 1 days after the onset of signs, respectively), p<0.0001. PK/PD modeling and simulation was pivotal all through the drug growth and emergency use authorization course of.

Extending conventional antibody therapies: Novel discoveries in immunotherapy and medical functions

Immunotherapy has been properly considered one of many safer and antigen-specific anti-cancer therapies in comparison with first-generation chemotherapy. Since Coley’s discovery, researchers targeted on engineering novel antibody-based therapies. Together with synthetic and modified antibodies, similar to antibody fragments, antibody-drug conjugates, and artificial mimetics, the number of immunotherapy has been quickly increasing in the previous couple of many years.
A survey of pharmacokinetic bioanalytical methods in biosimilar biological license applications (BLAs) for the assessment of target and antidrug antibodies effects
Genetic and chemical modifications to monoclonal antibody have been introduced into academia, in vivo trials, and medical functions. Right here, we have now seemed round antibodies general. First, we elucidate the antibody construction and its cytotoxicity mechanisms. Second, sorts of therapeutic antibodies are introduced. Moreover, there’s a summarized record of US Meals and Drug Administration (FDA)-approved therapeutic antibodies and up to date medical trials.

Canine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-c-96T 96T
EUR 570
  • Should the Canine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Eq-48T 48T
EUR 360
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Eq-96T 96T
EUR 457
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-g-48T 48T
EUR 464
  • Should the Goat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-g-96T 96T
EUR 601
  • Should the Goat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Hu-48T 48T
EUR 239
  • Should the Human Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Hu-96T 96T
EUR 292
  • Should the Human Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Mouse Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Mu-48T 48T
EUR 328
  • Should the Mouse Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Mu-96T 96T
EUR 415
  • Should the Mouse Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-p-48T 48T
EUR 456
  • Should the Porcine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-p-96T 96T
EUR 590
  • Should the Porcine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Ra-48T 48T
EUR 334
  • Should the Rat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Ra-96T 96T
EUR 422
  • Should the Rat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Rb-48T 48T
EUR 337
  • Should the Rabbit Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Rb-96T 96T
EUR 426
  • Should the Rabbit Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-b-48Tests 48 Tests
EUR 473

Bovine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-b-96Tests 96 Tests
EUR 654

Canine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-c-48Tests 48 Tests
EUR 455

Canine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-c-96Tests 96 Tests
EUR 629

Equine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Eq-48Tests 48 Tests
EUR 358

Equine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Eq-96Tests 96 Tests
EUR 490

Goat Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-g-48Tests 48 Tests
EUR 482

Goat Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-g-96Tests 96 Tests
EUR 667

Human Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Hu-48Tests 48 Tests
EUR 216

Human Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Hu-96Tests 96 Tests
EUR 287

Mouse Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Mu-48Tests 48 Tests
EUR 321

Mouse Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Mu-96Tests 96 Tests
EUR 438

Porcine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-p-48Tests 48 Tests
EUR 473

Porcine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-p-96Tests 96 Tests
EUR 654

Rat Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Ra-48Tests 48 Tests
EUR 328

Rat Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Ra-96Tests 96 Tests
EUR 447

Rabbit Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Rb-48Tests 48 Tests
EUR 331

Rabbit Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Rb-96Tests 96 Tests
EUR 451

Bovine Immunoglobulin G (IgG) ELISA Kit
RD-IgG-b-48Tests 48 Tests
EUR 453

Bovine Immunoglobulin G (IgG) ELISA Kit
RD-IgG-b-96Tests 96 Tests
EUR 625

Porcine Immunoglobulin G (IgG) ELISA Kit
RD-IgG-p-48Tests 48 Tests
EUR 453

Porcine Immunoglobulin G (IgG) ELISA Kit
RD-IgG-p-96Tests 96 Tests
EUR 625

Rat Immunoglobulin G (IgG) ELISA Kit
RD-IgG-Ra-48Tests 48 Tests
EUR 314

Rat Immunoglobulin G (IgG) ELISA Kit
RD-IgG-Ra-96Tests 96 Tests
EUR 428

Guinea pig Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Gu-48T 48T
EUR 315
  • Should the Guinea pig Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Guinea pig Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Gu-96T 96T
EUR 396
  • Should the Guinea pig Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Guinea pig Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Gu-48Tests 48 Tests
EUR 305

Guinea pig Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-Gu-96Tests 96 Tests
EUR 415

IgG
A00062 6 ml
EUR 108

IgG
A00062.0025 25 ml
EUR 252

IgG
A20062 2 ml
EUR 79

Rabbit IgG
31-1007 1 g
EUR 350
Description: Purified IgG from rabbit serum

Porcine IgG
31-1008 1 g
EUR 268
Description: Purified Porcine IgG protein

Bovine IgG
31-AB20 50 mg
EUR 220
Description: Purified Bovine IgG

Goat IgG
31-AG15 1 gram
EUR 570
Description: Purified Goat IgG

Mouse IgG
31-AM15 10 mg
EUR 215
Description: Purified Mouse IgG

Mouse IgG
31-AM15S 10 mg
EUR 130
Description: Purified Mouse IgG

Sheep IgG
31-AS25 100 mg
EUR 345
Description: Purified Sheep IgG

Dog IgG
31C-CH0401L 5 mg
EUR 175
Description: Purified Dog IgG

Pig IgG
31C-CH1401L 10 mg
EUR 198
Description: Purified Pig IgG

Donkey IgG
31C-CH1601 10 mg
EUR 236
Description: Purified Donkey IgG

Rabbit IgG
31R-1049 10 mg
EUR 136
Description: Purified Rabbit IgG

Sheep IgG
31R-1050 20 mg
EUR 136
Description: Purified Sheep IgG

Goat IgG
31R-1051 10 mg
EUR 136
Description: Purified Goat IgG

Rabbit IgG
31R-AR002 25 mg
EUR 381
Description: Purified Rabbit IgG

IgG antibody
10-2705 1 mg
EUR 133
Description: Mouse Monoclonal IgG antibody

Mouse IgG
1265-100
EUR 153

Mouse IgG
1265-1000
EUR 370

Rabbit IgG
1268-100
EUR 153

Rabbit IgG
1268-1000
EUR 370

Human IgG
1269-100
EUR 153

Human IgG
1269-1000
EUR 370

IgG Protein
abx069984-1g 1 g
EUR 1650
  • Shipped within 5-10 working days.

Pig IgG
E3M00001 200ul
EUR 408

Human IgG
E3M00002 200ul
EUR 408

Cow IgG
E3M00003 200ul
EUR 408

Mouse IgG
E61I007 1mg
EUR 343

Human IgG
E61I008 1mg
EUR 343

Rabbit IgG
E61I018 1mg
EUR 343

Sheep IgG
E61I019 1mg
EUR 343

Pig IgG
E61I023 1mg
EUR 343

Horse IgG
E61I024 1mg
EUR 343

IgG Antibody
1-CSB-PA00760E0Gp
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against IgG. Recognizes IgG from Goat. This antibody is Unconjugated. Tested in the following application: ELISA

IgG Antibody
1-CSB-PA00770E0Gp
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against IgG. Recognizes IgG from Goat. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

IgG Antibody
1-CSB-PA00780E0Gp
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against IgG. Recognizes IgG from Human. This antibody is Unconjugated. Tested in the following application: ELISA

IgG Antibody
1-CSB-PA00790E0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against IgG. Recognizes IgG from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Rat IgG
M1101-100
EUR 153

Rat IgG
M1101-1000
EUR 370

Goat IgG
M1102-100
EUR 153

Goat IgG
M1102-1000
EUR 370

GAP43 (IgG)
MO22171 100 µl
EUR 435

Bovine IgG
QY-E60066 96T
EUR 426

human papillomavirus IgG,HPV-IgG ELISA Kit
201-12-1103 96 tests
EUR 440
  • This papillomavirus IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Adenovirus IgG,ADV-IgG ELISA Kit
201-12-1768 96 tests
EUR 440
  • This Adenovirus IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human measlesvirus IgG,MV IgG ELISA Kit
201-12-1773 96 tests
EUR 440
  • This measlesvirus IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Leptospira IgG,Lep IgG ELISA Kit
201-12-1798 96 tests
EUR 440
  • This Leptospira IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Rotavirus IgG,RV IgG ELISA Kit
201-12-2138 96 tests
EUR 440
  • This Rotavirus IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Infectiousmononucleosis IgG?IM-IgG ELISA Kit
201-12-2181 96 tests
EUR 440
  • This Infectiousmononucleosis IgG?IM-IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Rabbit Anti-Human IgG (Fc) IgG, unlabeled
10119-R 0.5 mg
EUR 141

Goat Anti-Human IgG (Fc) IgG, unlabeled
10119 1 mg
EUR 202

Goat Anti-Human IgG (Fc) IgG, unlabeled
10119-2 1 mg
EUR 225

Goat Anti-Mouse IgG (Fc) IgG, unlabeled
40151-UL 1 mg
EUR 213

HDV-IgG hepatitis D IgG ELISA test
88 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HDV-IgG hepatitis D IgG

Human Papillomavirus IgG (HPV IgG) ELISA Kit
abx052750-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Hantavirus IgG (HV-IgG) ELISA Kit
abx055454-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Mouse Hantavirus IgG (HV-IgG) ELISA Kit
abx055496-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Lipopolysaccharides IgG (LPS IgG) ELISA Kit
abx257276-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Human LPS IgG(lipopolysaccharide IgG) ELISA Kit
EH4142 96T
EUR 524.1
  • Detection range: 1.563-100 ng/ml
Description: Method of detection: Indirect ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Lebtospira IgG/ Rat Lebtospira IgG ELISA Kit
ELA-E1279r 96 Tests
EUR 886

Hp-IgG/ Rat Hp- IgG ELISA Kit
ELA-E1387r 96 Tests
EUR 886

PV-IgG/ Rat PV- IgG ELISA Kit
ELA-E1659r 96 Tests
EUR 886

Igg-2a/ Rat Igg-2a ELISA Kit
ELI-42016r 96 Tests
EUR 886

Goat Anti-HIV gp120 IgG (poly) IgG
AB-16150 100 ul
EUR 445

Goat Anti-HIV gp41 IgG (poly) IgG
AB-16160 100 ul
EUR 445

Rabbit OVA IgG(Ovalbumin IgG) ELISA Kit
ERB0151 96T
EUR 567.6
  • Detection range: 3.125-200 ng/ml
Description: Method of detection: Indirect ELISA;Reacts with: Rabbit;Sensitivity: 1.875 ng/ml

Human Adenovirus IgG(ADV-IgG)ELISA Kit
GA-E1784HM-48T 48T
EUR 289

Human Adenovirus IgG(ADV-IgG)ELISA Kit
GA-E1784HM-96T 96T
EUR 466

Human measlesvirus IgG(MV IgG)ELISA Kit
GA-E1789HM-48T 48T
EUR 289

Human measlesvirus IgG(MV IgG)ELISA Kit
GA-E1789HM-96T 96T
EUR 466

Human Leptospira IgG(Lep IgG)ELISA Kit
GA-E1814HM-48T 48T
EUR 289

Human Leptospira IgG(Lep IgG)ELISA Kit
GA-E1814HM-96T 96T
EUR 466

Human papillomavirus IgG(HPV-IgG)ELISA Kit
GA-E1119HM-48T 48T
EUR 289

Human papillomavirus IgG(HPV-IgG)ELISA Kit
GA-E1119HM-96T 96T
EUR 466

Mouse Leptospira IgG(Lep IgG)ELISA Kit 　
GA-E0170MS-48T 48T
EUR 336

Mouse Leptospira IgG(Lep IgG)ELISA Kit 　
GA-E0170MS-96T 96T
EUR 534

Rat Leptospira IgG(Lep IgG)ELISA Kit
GA-E0268RT-48T 48T
EUR 317

Rat Leptospira IgG(Lep IgG)ELISA Kit
GA-E0268RT-96T 96T
EUR 496

Rabbit Leptospira IgG,Lep IgG ELISA Kit
GA-E0125RB-48T 48T
EUR 326

Rabbit Leptospira IgG,Lep IgG ELISA Kit
GA-E0125RB-96T 96T
EUR 524

Human Adenovirus IgG(ADV-IgG)ELISA Kit
QY-E00884 96T
EUR 361

Human papillomavirus IgG(HPV-IgG)ELISA Kit
QY-E01725 96T
EUR 361

Human measlesvirus IgG(MV IgG)ELISA Kit
QY-E02206 96T
EUR 361

Human Rotavirus IgG(RV IgG)ELISA Kit
QY-E02213 96T
EUR 361

Human Leptospira IgG(Lep IgG)ELISA Kit
QY-E03346 96T
EUR 361

Human Infectiousmononucleosis IgG(IM-IgG)ELISA Kit
QY-E03998 96T
EUR 361

Human Anti-tissue transglutaminase IgG(tTG-IgG)
QY-E05392 96T
EUR 361

Human dsDNA IgG(dsDNA IgG) ELISA Kit
QY-E05613 96T
EUR 361

Rat Infectiousmononucleosis IgG(IM-IgG)ELISA Kit
QY-E10628 96T
EUR 361

Rat Leptospira IgG(Lep IgG)ELISA Kit
QY-E11384 96T
EUR 361

Mouse Infectiousmononucleosis IgG(IM-IgG)ELISA Kit
QY-E20785 96T
EUR 361

Mouse Leptospira IgG(Lep IgG)ELISA Kit
QY-E20903 96T
EUR 361

Rabbit Leptospira IgG,Lep IgG ELISA Kit
QY-E30174 96T
EUR 374

Canine Leptospira IgG(Lep IgG)ELISA Kit
QY-E70163 96T
EUR 426

Goat Anti-Hamster IgG (H+L)-HRP conjugate (Syrian) IgG (Syrian) IgG
80320 1 ml
EUR 202

Human Cytomegalovirus IgG / IgM, Toxoplasma IgG / IgM, Rubella IgG Rapid Test Kit
abx092078-20tests 20 tests
EUR 342
  • Shipped within 5-12 working days.

Donkey IgG (non-immune, isotype control) IgG, purified
20015-10 10 mg
EUR 286

Human Helicobacter pylori IgG ,Hp-IgG ELISA Kit
201-12-1340 96 tests
EUR 440
  • This Helicobacter pylori IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Japanese Encephalitis IgG,JE IgG ELISA Kit
201-12-1586 96 tests
EUR 440
  • This Japanese Encephalitis IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Chlamydia pneumoniae IgG,Cpn IgG ELISA Kit
201-12-2076 96 tests
EUR 440
  • This Chlamydia pneumoniae IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human dengue fever IgG,DF-IgG ELISA Kit
201-12-2157 96 tests
EUR 440
  • This dengue fever IgG ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Rabbit Anti-Sheep IgG (Fc) IgG, aff pure
30619 1 mg
EUR 213

Goat Anti-Human IgG (Fc) IgG-HRP Conjugate
10119-HP 0.5 ml
EUR 213

Mouse Monoclonal Anti-Human IgG (Fc) IgG, unlabeled
10118-UL 0.25 mg
EUR 225

Goat Anti-Turkey IgG (H+L) IgG, Unlabeled
60600-UL 1 mg
EUR 263

Goat Anti-Mouse IgG (Fc) IgG-Biotin Conjugate
40151-BT 1 ml
EUR 225

Goat Anti-Mouse IgG (Fc) IgG-FITC Conjugate
40151-FITC 1 ml
EUR 225

Goat Anti-Mouse IgG (Fc) IgG-HRP Conjugate
40151-HRP 1 ml
EUR 225

Goat Anti-Cat IgG-Fc-IgG-HRP conjugate
71030-HP 0.5 ml
EUR 225

HEV-IgG CE Hepatitis E IgG ELISA test
91 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HEV-IgG CE Hepatitis E IgG

Rat Helicobacter Pylori IgG (Hp IgG) CLIA Kit
abx197121-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Human Adenovirus Antibody IgG (ADV IgG) ELISA Kit
abx052155-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Poliomyelitis Virus IgG (PV-IgG) ELISA Kit
abx052879-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Helicobacter Pylori IgG (Hp-IgG) ELISA Kit
abx053259-96tests 96 tests
EUR 637
  • Shipped within 5-10 working days.

Mouse Helicobacter Pylori IgG (Hp-IgG) ELISA Kit
abx053260-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Chicken Japanese Encephalitis IgG (JE IgG) ELISA Kit
abx053476-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Japanese Encephalitis IgG (JE IgG) ELISA Kit
abx053477-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Chikungunya Virus IgG (CHIKV-IgG) ELISA Kit
abx054994-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Human Dengue Virus IgG (DV-IgG) ELISA Kit
abx055294-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.

Mouse Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx254641-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Rat Helicobacter Pylori IgG (Hp-IgG) ELISA Kit
abx255715-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Human Rheumatoid Factor IgG (RF-IgG) ELISA Kit
abx257314-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Human Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx253447-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

Human RF-IgG(Rheumatoid Factor IgG) ELISA Kit
EH4269 96T
EUR 524.1
  • Detection range: 3.125-200IU/ml
Description: Method of detection: Indirect ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875IU/ml

Human ACA-IgG(Anti-Cardiolipin IgG) ELISA Kit
EH0478 96T
EUR 524.1
  • Detection range: 3.125-200 ng/ml
  • Alias: ACA-IgG(Anti-Cardiolipin IgG)
Description: Method of detection: Indirect ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Chicken Japanese Encephalitis IgG,JE IgG ELISA Kit
CN-00826C1 96T
EUR 471

Chicken Japanese Encephalitis IgG,JE IgG ELISA Kit
CN-00826C2 48T
EUR 322

Rat Helicobacter pylori IgG,Hp-IgG ELISA Kit
CN-01679R1 96T
EUR 471

Rat Helicobacter pylori IgG,Hp-IgG ELISA Kit
CN-01679R2 48T
EUR 322

Mouse Helicobacter pylori IgG,Hp-IgG ELISA Kit
CN-02551M1 96T
EUR 467

Mouse Helicobacter pylori IgG,Hp-IgG ELISA Kit
CN-02551M2 48T
EUR 316

Monkey Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx359940-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Pig Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx361882-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Rabbit Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx362353-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Human Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx354313-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Mouse Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx354531-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Rat Helicobacter Pylori IgG (Hp IgG) ELISA Kit
abx354581-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Chicken Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx355873-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Sheep Anticardiolipin Antibody IgG (aCL IgG) ELISA Kit
abx364584-96tests 96 tests
EUR 926
  • Shipped within 5-12 working days.

Human Diphtheria Toxoid IgG (DT IgG) ELISA Kit
abx364847-96tests 96 tests
EUR 543
  • Shipped within 5-12 working days.

Human Measles Virus IgG (MV IgG) ELISA Kit
abx364849-96tests 96 tests
EUR 543
  • Shipped within 5-12 working days.

Human Tetanus Toxoid IgG (TT IgG) ELISA Kit
abx364850-96tests 96 tests
EUR 543
  • Shipped within 5-12 working days.

Human Mumps Virus IgG (MuV IgG) ELISA Kit
abx364851-96tests 96 tests
EUR 543
  • Shipped within 5-12 working days.

Human Adenovirus (ADV) IgG (ADV IgG) ELISA Kit
abx364854-96tests 96 tests
EUR 511
  • Shipped within 5-12 working days.
This assessment supplies a complete overview of each the overall perform of therapeutic antibodies and some major variations in growth, together with current introduction with the proposed mechanism of actions, and we introduce sorts of therapeutic antibodies, medical trials, and accredited business immunotherapeutic medication.
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